Results 61 to 70 of about 1,136,223 (342)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Relationship between periodontal disease and preterm low birth weight: systematic review
Introduction Periodontal disease is a neglected bacterial infection that causes destruction of the periodontium in pregnant women. Yet its impact on the occurrence of adverse pregnancy outcomes has not systematically evaluated and there is no clear ...
Amare Teshome, A. Yitayeh
semanticscholar +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Nutrition of low birth weight infants [PDF]
The article is concerned with the current state of nutrition of low birth weight infants. Anatomo-physiological features of digestive system of heterogeneous cohort of low birth weight infants are given. The article presents the description of metabolism
Kadymova I.I., Bochkova L.G.
doaj
Socioeconomic disparities in birth weights (BWs) are associated with lifelong differences in health and productivity. Understanding socioeconomic disparities in BW is presently of concern to develop public health interventions that promote a good start ...
L. Pei+4 more
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Low birth weight in Eastern Nigeria
Background: Low birth weight (LBW), a major contributing factor to neonatal mortality was studied in four major hospitals in four different Igbo-speaking states of Eastern Nigeria - University of Nigeria Teaching Hospital Enugu (UNTH), St.
G N Adimora, O Ejike, N K Chukwudi
doaj
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
A Study of Surrogate Parameters of Birth Weight
Research question : Which anthropometric parameter is correlating highly with birth weight? Can we use this parameter as a screening test for predicting birth weight? What is their cut-off value?
Kadam Y, Somaiya P, Kakade S
doaj
Low birth weight and birth weight status in Bangladesh: A systematic review and meta-analysis
The prevalence of low birth weight (LBW) is high in Bangladesh, but no study has collated recent estimates of LBW prevalence from throughout the country.
Shaikh Saijuddin+2 more
doaj +1 more source