Results 131 to 140 of about 2,032,538 (389)

High fluoride and low calcium levels in drinking water is associated with low bone mass, reduced bone quality and fragility fractures in sheep

open access: yesOsteoporosis International, 2014
SummaryChronic environmental fluoride exposure under calcium stress causes fragility fractures due to osteoporosis and bone quality deterioration, at least in sheep.
M. Simon   +9 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Distribution Principle of Bone Tissue [PDF]

open access: yesarXiv, 2009
Using the analytic and experimental techniques we present an exploratory study of the mass distribution features of the high coincidence of centre of mass of heterogeneous bone tissue in vivo and its centroid of geometry position. A geometric concept of the average distribution radius of bone issue is proposed and functional relation of this geometric ...
arxiv  

Microbiota and Bone - Treatment Studies of Probiotics and Synbiotics on Osteoporosis in Mice [PDF]

open access: yes
Osteoporosis is a disease with low bone mass and an increased fracture risk. One in two women and one in four men in Sweden will experience an osteoporotic fracture. The aim of this thesis is to identify new gut microbiota-based preventive treatments for
Lawenius, Lina
core   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

Efficacy and safety of oral recombinant calcitonin tablets in postmenopausal women with low bone mass and increased fracture risk: a randomized, placebo-controlled trial

open access: yesOsteoporosis International, 2014
SummaryThe effect of an investigational oral calcitonin tablet upon bone mineral density (BMD) of the spine was investigated in postmenopausal women with low bone mass and at increased risk of fracture.
N. Binkley   +3 more
semanticscholar   +1 more source

Bone Mineral Density at the Distal Radius in Female Collegiate Ice Hockey Athletes [PDF]

open access: yes, 2014
Honorable Mention 2014 Denman Undergraduate Research Forum in HealthBackground: Low bone density in the distal radius has been associated with higher risk for fracture.
Allis, Rebecca
core  

Modeling the Multiple Myeloma Vicious Cycle: Signaling Across the Bone Marrow Microenvironment [PDF]

open access: yesarXiv, 2015
Multiple myeloma is a plasma cell cancer that leads to a dysregulated bone remodeling process. We present a partial differential equation model describing the dynamics of bone remodeling with the presence of myeloma tumor cells. The model explicitly takes into account the roles of osteoclasts, osteoblasts, precursor cells, stromal cells, osteocytes ...
arxiv  

Low-Bone-Mass Phenotype of Deficient Mice for the Cluster of Differentiation 36 (CD36)

open access: yesPLoS ONE, 2013
Bone tissue is continuously remodeled by bone cells and maintenance of its mass relies on the balance between the processes of resorption and formation. We have reported the expression of numerous scavenger receptors, namely scavenger receptor (SR) class
Olha Kevorkova   +5 more
semanticscholar   +1 more source

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone [PDF]

open access: yes, 2019
Mineralized bone forms when collagen-containing osteoid accrues mineral crystals. This is initiated rapidly (primary mineralization), and continues slowly (secondary mineralization) until bone is remodeled. The interconnected osteocyte network within the
Vrahnas, Christina   +17 more
core   +1 more source

Home - About - Disclaimer - Privacy