The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism [PDF]
, 2015 The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased ...
COLUZZI, FLAMINIA +3 more
core +3 more sources
Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment. [PDF]
PLoS ONE, 2012 Trisomy 21 affects virtually every organ system and results in the complex clinical presentation of Down syndrome (DS). Patterns of differences are now being recognized as patients' age and these patterns bring about new opportunities for disease ...
Tristan W Fowler +13 more
doaj +1 more source
Reduced energy availability: implications for bone health in physically active populations [PDF]
, 2017 Purpose: The present review critically evaluates existing literature on the effects of short- and long-term low energy availability (EA) on bone metabolism and health in physically active individuals.
Dolan, E +3 more
core +1 more source
Factors associated with low bone density in patients referred for assessment of bone health [PDF]
, 2013 Background: To identify factors that predict low bone mineral density (BMD) in pediatric patients referred for dual-energy x-ray absorptiometry assessments.
Giancaterino, Courtney +3 more
core +1 more source
A retrospective analysis of longitudinal changes in bone mineral content in cystic fibrosis [PDF]
, 2017 Background: We aimed to describe the longitudinal changes in bone mineral content and influencing factors, in children with cystic fibrosis (CF). Methods: One hundred children (50 females) had dual X-ray absorptiometry (DXA) performed.
Ahmed, Syed Faisal +7 more
core +1 more source
Food & Nutrition Research, 2013 Background: The intake of dehydrated nopal (DN) at a high stage of maturity along with high calcium content could improve bone mineral density (BMD) and calciuria and thus prevent osteoporosis.
María de los Angeles Aguilera-Barreiro +5 more
doaj +1 more source
Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation. [PDF]
PLoS ONE, 2018 Gfi1 is a key molecule in hematopoietic lineage development and mutations in GFI1 cause severe congenital neutropenia (SCN). Neutropenia is associated with low bone mass, but the underlying mechanisms are poorly characterized.
Sven Geissler +11 more
doaj +1 more source
Impact of Genetics on Low Bone Mass in Adults
Journal of Bone and Mineral Research, 2008 Abstract Low bone mass in adults is a major risk factor for low-impact fractures and is considered of complex origin because of interaction of environmental and genetic factors, each with modest effect. The objective was to assess the relative impact of genetics and environment and quantify the risk in relatives of osteopenic individuals.
Gunnar, Sigurdsson +4 more
openaire +2 more sources
Non-neural phenotype of spinal and bulbar muscular atrophy: Results from a large cohort of Italian patients [PDF]
, 2016 Objective: To carry out a deep characterisation of the main androgen-responsive tissues involved in spinal and bulbar muscular atrophy (SBMA). Methods: 73 consecutive Italian patients underwent a full clinical protocol including biochemical and hormonal ...
Angelini, Lorenzo +37 more
core +1 more source
Bone Health in Children With Risk Factors for Low Bone Mass [PDF]
, 2022 Abstract Purpose: To describe clinical and biological characteristics of pediatric patients with at least one risk factor (RF) for low bone mass for chronological age (LBMca)/childhood osteoporosis (cOP) and to assess its influence on bone mineral density (BMD).Methods: Patients between 2 and 20 years of age with at least 1 RF were recruited ...
Berta Magallares +14 more
openaire +1 more source