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Levosimendan for the Low Cardiac Output Syndrome after Cardiac Surgery
New England Journal of Medicine, 2017The low cardiac output syndrome complicates 1 in 10 coronary bypass operations and is associated with a heightened risk of perioperative death.1 The pathophysiology of this syndrome is complex, with likely contributions from reperfusion injury, systemic inflammation induced by cardiopulmonary bypass, and pulmonary and systemic vasoconstriction.2 ...
Akshay S, Desai, John A, Jarcho
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Low cardiac output syndrome in children
Current Anaesthesia & Critical Care, 2005Clinicians caring for critically ill children will commonly encounter low cardiac output states, especially after cardiac surgery. Anticipation and prevention can go some way to reducing morbidity and mortality. This article outlines the causes and assessment of this syndrome.
Jones, Bryn +3 more
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Pathophysiology of Post-Operative Low Cardiac Output Syndrome
Current Vascular Pharmacology, 2015Low cardiac output syndrome frequently complicates the post-operative care of infants and children following cardiac surgery. The onset of low cardiac output follows a predictable course in the hours following cardiopulmonary bypass, as myocardial performance declines in the face of an elevated demand for cardiac output.
Conrad L, Epting +3 more
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Levosimendan Reduces Mortality and Low Cardiac Output Syndrome in Cardiac Surgery
The Thoracic and Cardiovascular Surgeon, 2019Abstract Background There has been conflicting evidence concerning the effect of levosimendan on clinical outcomes in patients undergoing cardiac surgery. Therefore, we performed a systematic review and conducted this meta-analysis to provide evidence for/against the administration of levosimendan in cardiac surgery patients ...
Thorsten C. W. Wahlers +11 more
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Management of Postoperative Low Cardiac Output Syndrome
Critical Care Nursing Quarterly, 2002The management of the infant with congenital heart disease is a multidisciplinary collaborative effort that is individualized to each patient. Low cardiac output is frequently seen in the postoperative infant with arrhythmia, preload, afterload, and contractility alterations; it can be a significant complication after open heart surgery. The management
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Pharmacologic therapy of low output syndromes after cardiac surgery
Archives Internationales de Physiologie et de Biochimie, 1984With the advancement of surgical techniques and myocardial protection we can expect that patients previously felt to be inoperable because of poor ventricular function will be surgical candidates. This group of patients will on occasion develop severe left ventricular dysfunction in the peri-operative period.
R A, Goldstein, T J, Byrnes, S A, Geraci
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Preliminary Results with Amrinone in Perioperative Low Cardiac Output Syndrome
The Thoracic and Cardiovascular Surgeon, 1987The hemodynamic parameters of 24 cardiosurgical patients with low cardiac output syndrome (LCOS) after weaning from bypass were evaluated retrospectively. These patients were additionally treated with amrinone if the conventional therapy with catecholamines and vasodilators did not reach satisfying hemodynamic results.
M, Günnicker, W, Hess
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Inodilators in the Management of Low Cardiac Output Syndrome After Pediatric Cardiac Surgery
Current Vascular Pharmacology, 2015Postoperative low cardiac output syndrome has been shown to have both a central and a peripheral vascular involvement. Therefore, inodilators which provide with a combination of positive inotropic and vasodilating therapy, conceptually should be an ideal form of treatment. However, contradictory data on these drugs exist.
Angela, Ferrer-Barba +2 more
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Pathogenesis of the low cardiac output syndrome in postresuscitation states
Bulletin of Experimental Biology and Medicine, 1976Acute hypervolemia induced in experiments on dogs by infusion of dextran, did not produce decompensation of the circulation in animals whose cardiac output was sharply depressed in the postresuscitation period after circulatory arrest lasting 15 min.
I. E. Trubina, A. V. Volkov
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Intra-Aortic Balloon Pumping for Low Cardiac Output Syndromes
Surgical Clinics of North America, 1975Since the prototype of the intra-aortic balloon pump was introduced, data accumulated from work with animals and in humans have begun to establish those clinical conditions amenable to partial temporary circulation support and to define the physiologic limits of this support system.
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