Results 191 to 200 of about 1,515,008 (404)

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Oxidized or acetylated low density lipoproteins are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A type I/II gene. [PDF]

, 1997
Wenhua Ling, Marilee Lougheed, Hiroaki Suzuki, A.M.J. Buchan, Takeshi Kodama, U P Steinbrecher   +5 more
openalex   +1 more source

Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis

British medical journal, 2003
M. Law, N. Wald, A. Rudnicka
semanticscholar   +1 more source

Low Density Lipoprotein [PDF]

Journal of Clinical Investigation, 1978
A. Sniderman, D. Thomas, D. Marpole, B. Teng   +3 more
openaire   +1 more source

Lysyl Oxidase Reduces Neutrophil Extravasation in Response to P. aeruginosa in an Infection‐on‐a‐Chip Model

Advanced NanoBiomed Research, EarlyView.
Lysyl oxidase crosslinking of type I collagen decreases neutrophil extravasation through an endothelium during the initial response to P. aeruginosa. This decrease in extravasation is likely due to the increase in VE‐cadherin expression between endothelial cells seeded on LOX‐crosslinked collagen hydrogels.
Christopher J. Calo, Tanvi Patil, Josephine Fouts, Eric L. Ginter, Margaret Radke, Hannah K. Weppner, Justin M. Owens, Laurel E. Hind   +7 more
wiley   +1 more source

The Low Density Lipoprotein Receptor-related Protein Complexes with Cell Surface Heparan Sulfate Proteoglycans to Regulate Proteoglycan-mediated Lipoprotein Catabolism

, 2003
Larissa Wilsie, Robert A. Orlando
openalex   +1 more source

Pravastatin inhibits cellular cholesterol synthesis and increases low density lipoprotein receptor activity in macrophages: in vitro and in vivo studies. [PDF]

, 1994
S Keidar, M Aviram, Irit Maor, J. Oiknine, J.G. Brook   +4 more
openalex   +1 more source

Clinical efficacy and safety of evolocumab for low-density lipoprotein cholesterol reduction

, 2016
Courtney A Henry, Ronald A Lyon, Hua Ling Department of Pharmacy Practice, School of Pharmacy, Hampton University, Hampton, VA, USA Abstract: Multiple categories of medications have been developed to manage lipid profiles and reduce the risk of ...
Lyon RA, Ling H, Henry CA
core  

Oxidized low‐density lipoprotein in inflammation‐driven thrombosis

Journal of Thrombosis and Haemostasis, 2018
G. Obermayer, T. Afonyushkin, T. Afonyushkin, C. Binder, C. Binder   +4 more
semanticscholar   +1 more source

Biomimetic Nanoparticle Delivering Colchicine to Target Endothelial Inflammation for Atherosclerosis Treatment

Advanced NanoBiomed Research, EarlyView.
Platelet membrane‐coated layered double hydroxide nanoparticles were engineered to target inflamed endothelium at early‐stage atherosclerosis and enhance therapeutic efficacy. The biomimetic platform improves stability, immune escape, and inflamed vascular cell targeting, resulting in reduced oxidative stress and downregulated adhesion molecules.
Xiuwen Zhang, Lingqing Zong, Ashish Misra, Sanjay Patel, Zi Gu   +4 more
wiley   +1 more source