Results 361 to 370 of about 1,515,008 (404)

Antioxidant effect of high-density lipoproteins in peroxidation of low-density lipoproteins

Bulletin of Experimental Biology and Medicine, 1987
It has been shown that in the solution of low density lipoproteins (LDL) during their incubation at 37 degrees C the turbidity and concentration of malondialdehyde was increased, as compared to that observed at 4 degrees C. Both parameters were slowed down by the addition of high density lipoproteins (HDL) into the medium.
A N, Klimov, L A, Kozhemiakin, V M, Pleskov, L I, Andreeva   +3 more
openaire   +2 more sources

Low-Density Lipoprotein Density and Atherosclerosis

JAMA, 1994
To provide an overview of the relationship between low-density lipoprotein (LDL) density and coronary artery disease and to examine this relationship in terms of lipid peroxidation and the atherogenic remnant hypothesis.English-language studies and reviews pertaining to LDL composition and size were identified through a MEDLINE search and reference ...
openaire   +2 more sources

Receptors for modified low-density lipoproteins on human endothelial cells: different recognition for acetylated low-density lipoprotein and oxidized low-density lipoprotein

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1991
We examined the uptake pathway of acetylated low-density lipoprotein and oxidatively modified LDL (oxidized LDL) in human umbilical vein endothelial cells in culture. Proteolytic degradation of 125I-labeled Ac-LDL or Ox-LDL in the confluent monolayer of human endothelial cells was time-dependent and showed saturation kinetics in the dose-response ...
N, Kume, H, Arai, C, Kawai, T, Kita
openaire   +2 more sources

Low density lipoprotein turnover in swine

Canadian Journal of Biochemistry, 1978
The catabolism of intravenously injected 125I-labelled low density lipoproteins (LDL) was followed in normal miniature swine for 2 weeks. When compared with the two-exponential model, the decay curve of the plasma radioactivity associated with the LDL fraction was best described by a three-exponential model. In this system, the half-lives were 4.5 ± 3.
Y L, Marcel, A C, Nestruck, M, Bergseth, M, Bidallier, W T, Robinson, D, Jeffries   +5 more
openaire   +2 more sources

High-density lipoprotein, low-density lipoprotein and coronary artery disease

The American Journal of Cardiology, 1990
Lipoprotein cholesterol data from the Framingham Heart Study show that low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol levels are important in determining risk for coronary artery disease (CAD). Increased LDL and decreased HDL cholesterol levels are associated with an increase in CAD.
openaire   +2 more sources

Desialylated low density lipoproteins and atherosclerosis

1992
Oxidative modification of LDL is accompanied by a number of compositional and structural changes, now well known. In addition, other atherogenic modifications of LDL exist, such as desialylation. The present article summarizes the recent data related to desialylated LDL and to the presence of these LDL in blood plasma of patients with coronary ...
N, Dousset, J C, Dousset, M L, Soléra, P, Valdiguié   +3 more
openaire   +2 more sources

The catabolism of very low density lipoproteins

Canadian Journal of Biochemistry and Cell Biology, 1985
The lipolysis of very low density lipoproteins (VLDL) in vitro is a useful model for the study of the process of conversion of this triacylglycerol rich lipoprotein into low (LDL) and high (HDL) density lipoproteins. Data is reviewed to show that a portion of surface cholesterol and phospholipid which becomes redundant during lipolysis is lost from ...
openaire   +2 more sources

Organ Specific Metabolism of Low Density Lipoprotein and High Density Lipoprotein

1984
Recent data indicate that the kidneys are the most important organ for the catabolism of HDL-apolipoproteins in the rat. This catabolic process is probably initiated by a specific HDL receptor in kidney membranes. However, it is unlikely that receptor-mediated endocytosis of intact HDL is involved in HDL-apolipoprotein degradation by kidneys, since HDL-
openaire   +2 more sources

The low-density lipoprotein pathway and its relation to atherosclerosis.

Annual Review of Biochemistry, 1977
J. Goldstein, M. Brown
semanticscholar   +1 more source

Low-density lipoprotein subclass patterns and risk of myocardial infarction.

Journal of the American Medical Association (JAMA), 1988
M. Austin, J. Breslow, C. Hennekens, J. Buring, W. Willett, R. Krauss   +5 more
semanticscholar   +1 more source