Results 231 to 240 of about 10,282,441 (287)

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

open access: yesAdvanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li   +8 more
wiley   +1 more source

Low-Dose Radiation and Leukemia

New England Journal of Medicine, 1980
We investigated the effect of diagnostic and low-level therapeutic radiation (less than 300 rads to the bone marrow) on the development of leukemia. During this study, 138 patients with leukemia (representing all known incidence cases of leukemia in residents of Olmsted County, Minnesota, between 1955 and 1974) were each matched with two controls, and ...
A, Linos   +5 more
  +7 more sources

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