Results 111 to 120 of about 31,908 (302)
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Aerodynamic forces have often been proposedas a possible means to perform a variety of different attitude and orbit control manoeuvres in very low Earth orbits including pointing control, constellation and formation management, and re-entry interface ...
Rodríguez Donaire, Silvia +5 more
core +1 more source
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
A novel design concept for space-based polar remote sensing
Space-based remote sensing of the Earth is conducted from a fleet of spacecraft in two basic orbital positions, near-polar low-Earth orbits and geosynchronous orbits, with each offering its own advantages and disadvantages.
Macdonald, Malcolm +2 more
core
Low-thrust enabled highly non-Keplerian orbits in support of future Mars exploration
The technology of high specific impulse propulsion systems with low thrust is improving, opening up numerous possibilities for future missions applying continuous thrust to force a spacecraft out of a natural Keplerian orbit into a displaced non ...
Bosquillon de Frescheville, Francois +8 more
core +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Tipping Points of Space Debris in Low Earth Orbit
Global services like navigation, communication, and Earth observation have increased dramatically in the 21st century due to advances in outer space industries.
Keiko Nomura +6 more
doaj +1 more source

