Results 71 to 80 of about 32,070 (302)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
First In-orbit Experience of TerraSAR-X Flight Dynamics Operations [PDF]
, 2007 TerraSAR-X is an advanced synthetic aperture radar satellite system for scientific and commercial applications that is realized in a public-private partnership between the German Aerospace Center (DLR) and the Astrium GmbH.
Kiehling, Reinhard +11 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mission analysis and systems design of a near-term and far-term pole-sitter mission [PDF]
, 2014 This paper provides a detailed mission analysis and systems design of a near-term and far-term polesitter mission. The pole-sitter concept was previously introduced as a solution to the poor temporal resolution of polar observations from highly inclined,
Biggs, James +13 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Optimal trajectory design for interception and deflection of Near Earth Objects [PDF]
, 2010 Many asteroids and comets orbit the inner solar system; among them Near Earth Objects (NEOs) are those celestial bodies for which the orbit lies close, and sometimes crosses, the Earth's orbit.
Colombo, Camilla +2 more
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Demonstration of aerodynamic control manoeuvres in very low earth orbit using SOAR (Satellite for Orbital Aerodynamics Research) [PDF]
, 2019 Aerodynamic forces have often been proposedas a possible means to perform a variety of different attitude and orbit control manoeuvres in very low Earth orbits including pointing control, constellation and formation management, and re-entry interface ...
Rodríguez Donaire, Silvia +5 more
core +2 more sources
Passive Metasurface-Based Low Earth Orbit Ground Station Design
Tsinghua Science and TechnologyLow Earth Orbit (LEO) satellite communication is vital for wireless systems. The main challenges in designing LEO satellite ground stations include increasing the input signal strength to counteract severe path loss, and adaptively steering the direction
Hao Pan, Lili Qiu
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source