Results 141 to 150 of about 2,484,191 (321)

Self-consistent scattering description of transport in normal-superconductor structures

, 1996
We present a scattering description of transport in several normal-superconductor structures. We show that the related requirements of self-consistency and current conservation introduce qualitative changes in the transport behavior when the current in ...
A. Furusaki, A. Martin, A.F. Andreev, C. Bruder, C.J. Lambert, C.J. Lambert, C.J. Pethick, C.W.J. Beenakker, C.W.J. Beenakker, D.R. Heslinga, F. Sols, F. Sols, G. Baym, G. Baym, G.E. Blonder, J. Bardeen, J. Clarke, J. Sánchez-Cañizares, J. Sánchez-Cañizares, J. Sánchez-Cañizares, J.A. Melsen, J.G. Rodrigo, J.S. Langer, K.K. Likharev, M. Büttiker, M. Klapwijk, M. Poza, M. Tinkham, M. Tinkham, M.G. Blamire, P.F. Bagwell, P.G. de Gennes, R. Landauer, V. Hui, W.L. McMillan, Y. Takane, Y. Takane   +36 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Morphology--Cosmology Connection for X--Ray Clusters

, 1993
We employ N--body/$3D$ gas dynamic simulations of the formation of galaxy clusters to determine whether cluster X--ray morphologies can be used as cosmological constraints.
Evrard, August, Fabricant, Daniel, Geller, Margaret, Mohr, Joseph   +3 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The shapes of the circumstellar silicate features [PDF]

Around oxygen-rich stars the spectra of most long-period variables (LPV) show an excess infrared emission which is attributed to circumstellar silicate dust grains.
Little-Marenin, I. R., Price, S. D.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Transportation Energy Futures Series: Alternative Fuel Infrastructure Expansion: Costs, Resources, Production Capacity, and Retail Availability for Low-Carbon Scenarios

, 2013
W. Melaina, Garvin Heath, Debra Sandor, Darlene Steward, Laura Vimmerstedt, Ethan Warner, Karen Webster   +6 more
openalex   +4 more sources

Low Energy Availability in a Sleep-Low Training Study

Medicine & Science in Sports & Exercise, 2017
Samuel, Mettler, Beat, Müller, Judith, Haudum   +2 more
openaire   +3 more sources