Results 121 to 130 of about 1,044,650 (277)

Evaluation of Dynamic Daylight Metrics, Based on Weather, Location, Orientation and Daylight Availability [PDF]

, 2020
This paper demonstrates that it is possible to achieve 3 daylight credits of Leadership in Environmental and Energy Design version 4 (LEED v4) in all latitudes and orientations.
Beltran, Liliana, Liu, Di
core  

Dietary intake, energy availability, and power in men collegiate gymnasts

Frontiers in Sports and Active Living
IntroductionThe purpose was to examine the prevalence of low energy availability (LEA), explore dietary behaviors in men collegiate gymnasts (n = 14), and investigate the relationships between energy availability (EA), body composition, and plyometric ...
Nicholas M. Kuhlman, Margaret T. Jones, Margaret T. Jones, Andrew R. Jagim, Andrew R. Jagim, Meghan K. Magee, Luke Wilcox, Jennifer B. Fields, Jennifer B. Fields   +8 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The Athlete’s Body Image in the Context of Relative Energy Deficiency in Sport—A Scoping Review

Journal of Functional Morphology and Kinesiology
Background: Relative Energy Deficiency in Sport (REDs) results from an imbalance between energy intake and expenditure, leading to low energy availability (LEA) and impairments of physiological and/or psychological functions in female and male athletes ...
Tabea Ruscheck, Christine Kopp, Andreas M. Nieß, Daniel Haigis   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Risk and prevalence of Relative Energy Deficiency in Sport (REDs) among professional female football players

European Journal of Sport Science
A high prevalence of low energy availability (LEA) has been reported in female football players. This is of concern as problematic LEA may evolve into a syndromic pattern known as relative energy deficiency in sport (REDs).
Marcus S. Dasa, Oddgeir Friborg, Morten Kristoffersen, Gunn Pettersen, Jorn V. Sagen, Monica Klungland Torstveit, Jorunn Sundgot‐Borgen, Jan H. Rosenvinge   +7 more
doaj   +1 more source

The harder the prep, the harder the recovery: a qualitative exploration of physique athlete perspectives on competition weight loss and restoration

Journal of the International Society of Sports Nutrition
Background There is growing recognition of Low Energy Availability (LEA) symptoms in physique sports, however there are no clear recovery guidelines.
Claire Buechel, Kate Pumpa, Naroa Etxebarria, Michelle Minehan   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Effects of low energy availability on performance in male athletes: A scoping review

Journal of Science and Medicine in Sport
The primary aim of this study was to investigate the effects of low energy availability on different performance outcomes in male athletes. Secondary aims were to examine an assumed dose-response relationship and identify knowledge gaps.Scoping review.The electronic database PubMed was searched until the end of June 2023.
Tim, Hänisch, Andreas M, Nieß, Anja, Carlsohn   +2 more
openaire   +2 more sources