Results 101 to 110 of about 1,044,650 (277)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Options for solar thermal and heat recovery loop hybrid system design

, 2014
Integration of solar thermal energy into low temperature pinch processes, like dairy and food and beverage processes is more economic when combined with a Heat Recovery Loop (HRL) to form a hybrid inter-plant heat recovery system.
Walmsley, Michael R.W., Walmsley, Timothy Gordon, Atkins, Martin John, Neale, James R.   +3 more
core   +1 more source

Prevalence of Low Energy Availability (LEA) Risk in Division III Female Distance Athletes

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers' Association
OBJECTIVE The objective of this study was to explore the prevalence of LEA among division III female distance athletes.
Ciara Murphy
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Molecular Pathways Mediating Immunosuppression in Response to Prolonged Intensive Physical Training, Low-Energy Availability, and Intensive Weight Loss

Frontiers in Immunology, 2019
Exercise and exercise-induced weight loss have a beneficial effect on overall health, including positive effects on molecular pathways associated with immune function, especially in overweight individuals.
Heikki V. Sarin, Heikki V. Sarin, Ivan Gudelj, Jarno Honkanen, Jarno Honkanen, Johanna K. Ihalainen, Johanna K. Ihalainen, Arja Vuorela, Joseph H. Lee, Zhenzhen Jin, Joseph D. Terwilliger, Ville Isola, Juha P. Ahtiainen, Keijo Häkkinen, Julija Jurić, Gordan Lauc, Gordan Lauc, Kati Kristiansson, Kati Kristiansson, Juha J. Hulmi, Juha J. Hulmi, Markus Perola, Markus Perola   +22 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Energy-Aware Topology Control Strategy for Human-Centric Wireless Sensor Networks [PDF]

, 2014
The adoption of mobile and ubiquitous solutions that involve participatory or opportunistic sensing increases every day. This situation has highlighted the relevance of optimizing the energy consumption of these solutions, because their operation depends
Molina, C., Ochoa Delorenzi, Sergio, Ochoa, S., Rodrigo Santos, Carlos Molina, Santos, R., Roc Meseguer, Meseguer, Roc, Sergio Ochoa, Santos, Rodrigo, Meseguer Pallarès, Roc, Ochoa, Sergio, Meseguer, R., Santos, Rodrigo Martin, Sergio F. Ochoa, Molina, Carlos, Ochoa, Sergio F.   +16 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Making low-carbon energy available 24/7

Field Actions Science Reports, 2022
In the face of the challenges raised by the accelerating climate emergency, the question of digital’s environmental footprint is a major issue facing all the industry players. In response to this challenge, and in addition to a decarbonization drive set in motion several years ago, Google is running a program to ensure that all its data centers and ...
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source