Results 91 to 100 of about 13,400,617 (291)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Clinics and Practice, 2011 We present a rare case of internal carotid artery pseudoocclusion (ICAPO) in a 60-yearold male Caucasian patient who experienced a reversible sudden loss of vision of the right eye for 10 min followed by recurrent blurring of vision as well as dysarthria
Christoph Roehrer +6 more
doaj +1 more source
Nature, 1968 Introduction to the Dynamics of Rarefied Gases By V. P. Shidlovskiy Translated by Scripta Technica Inc. Translation edited by J. A. Laurmann. Pp. xvi + 168. (New York, Amsterdam and London: Elsevier, 1967.) 130s.
openaire +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Global assessment of agreement among streamflow projections using CMIP5 model outputs
Environmental Research Letters, 2014 Runoff outputs from 11 atmosphere–ocean general circulation models (AOGCMs) participating in the fifth phase of Coupled Model Intercomparison Project were used to evaluate the changes in streamflow and agreement among AOGCMs at the end of 21st century ...
Sujan Koirala +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Low flows : mechanisms, forecasts and climate change impacts [PDF]
, 2013 A research on low flows may seem controversial for a “wet” country protected by dykes and barriers. However, low flows in dry summers such as in 1976, 1985 and 2003 indicate that it may happen also in the Rhine basin. Improved medium-range and seasonal low fow forecasts are important as there is an increasing interest to account for low flow forecasts ...
openaire +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Effect of Oil on Flow Boiling Heat Transfer and Flow Patterns of CO2 in 11.2 mm Horizontal Smooth and Enhanced Tube [PDF]
, 2012 Flow boiling heat transfer characteristics of CO2 with and without oil were investigated experimentally in horizontal smooth and enhanced tubes with an inner diameter of 11.2 mm.
Hrnjak, Predrag S., Kim, Seongho
core +1 more source