Results 91 to 100 of about 10,612,844 (305)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Grade Inflation at the University of Hawaii-Manoa [PDF]

open access: yes
I found that the University has experienced modest grade inflation over the past twelve years but the rate of inflation has been considerably low relative to other universities. In addition, I failed to find clear evidence of a widening interdepartmental
Kwang Soo Cheong
core  

Desarrollando mercados rurales: El rol de la incertidumbre y la restricción crediticia [PDF]

open access: yes, 2005
El estudio evalúa cuáles son los factores más relevantes para que un pequeño productor agrícola demande asistencia técnica con el propósito de incursionar en mercados “dinámicos”; es decir, en mercados que puedan absorber cantidades crecientes de su ...
Escobal, Javier A   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Low-Grade Inflammation: Pathophysiological Mechanisms and Drug Targets in Irritable Bowel Syndrome with Diarrhea [PDF]

open access: yes
Baibai Ye,1 Ziyu Fu,1 Xin Zhou,1 Shengmei Wang,1 Linqi Ouyang,1 Zhen Chen,1 Guiming Deng1,2 1The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, People’s Republic of China; 2The Second Hospital of Hunan University of Chinese ...
Chen Z   +6 more
core  

The effectiveness of grade retention as an intervention strategy for academic failure [PDF]

open access: yes, 2001
Plan BOver the past decade there has been public and political pressure to improve the quality of education. Schools are being encouraged to adopt grade retention policies to help children who are falling behind academically.
Viland, Kelly Rochelle
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

How to Construct a Combined S-CO2 Cycle for Coal Fired Power Plant?

open access: yesEntropy, 2018
It is difficult to recover the residual heat from flue gas when supercritical carbon dioxide (S-CO2) cycle is used for a coal fired power plant, due to the higher CO2 temperature in tail flue and the limited air temperature in air preheater. The combined
Enhui Sun   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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