Results 121 to 130 of about 3,506,686 (362)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Kinetics roasting low grade concentrates molybdenite [PDF]

, 2013
El molibdeno es un metal atractivo para la fabricación de aceros y fundiciones debido a que promueve un marcado endurecimiento, aumentando la resistencia mecánica cuando la aleación se somete a enfriamientos controlados en un rango de temperaturas ...
Bazan Brizuela, Vanesa Lucia, Brandaleze, Elena, Colque, Enzo   +2 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Resolving the “Thick-Wall Challenge” in Haematococcus pluvialis: From Metabolic Reprogramming to Clinical Translation

Microorganisms
Astaxanthin, derived from Haematococcus pluvialis, is a potent antioxidant with significant therapeutic potential. However, its large-scale commercialization is hindered by the “thick-wall challenge”, a phenomenon where the stress conditions required for
Tao Chen, Xun Zhu, Qiang Liao
doaj   +1 more source

OS5.6 Initial treatment strategy for presumed low-grade glioma: a preoperative perspective [PDF]

, 2016
Maarten M.J. Wijnenga, Tariq Mattni, Pim J. French, Geert-Jan Rutten, Sieger Leenstra, Fred Kloet, M. J. B. Taphoorn, Martin J. van den Bent, Marie‐Lise C. van Veelen, Arnaud J.P.E. Vincent   +9 more
openalex   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Does Money Matter? Regression-Discontinuity Estimates from Education Finance Reform in Massachusetts [PDF]

The paper studies a typical state-level education finance equalization scheme, and considers two questions. First, what fraction of state education aid is spent on schools?
Jonathan Guryan
core  

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Occurrence of Sesquioxide in a Mid-Low Grade Collophane-Sedimentary Apatite Ore from Guizhou, China [PDF]

, 2020
Jie Deng, Kecheng Zhang, Dongsheng He, Zhao Heng-qin, Rachid Hakkou, Mostafa Benzaazoua   +5 more
openalex   +1 more source