Results 121 to 130 of about 10,612,844 (305)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

New Analysis Method for Gold Occurrence in Carlin-type Gold Ore

Yankuang ceshi, 2013
Gold exists in the form of micro-super micro dispersed states in Carlin-type gold ores, which is in the form of rich organic matter. The gold occurrence state cannot be analyzed accurately or at best, can be roughly estimated by using the Mineral ...
SU Xiu-zhu, HUANG Zhi-hua, ZHONG Shui-ping, XU Tao, LIAO Zhan-pi, HUANG Li-juan   +5 more
doaj  

Elucidating the role of potassium in reaction kinetics and mechanism during degradative solvent extraction process of cellulose

International Journal of Coal Science & Technology
The degradative solvent extraction (DSE) method has been proven effective in simultaneous deoxygenation and deashing of lignocellulosic biomass. However, the effects of K, the most abundant metallic element in biomasses, still remain unclear.
Zhanbo Huang, Qintao Sun, Xianqing Zhu, Chaoran Duan, Zhenzhong Hu, Yun Huang, Ao Xia, Xun Zhu, Qiang Liao   +8 more
doaj   +1 more source

Topology Optimization of Liquid-Cooled Heat Sinks for High-Power-Density IGBT Modules

Applied Sciences
High-power-density insulated gate bipolar transistor (IGBT) modules in new energy vehicles require efficient heat dissipation and good temperature uniformity.
Jinlie Li, Tianyu Ma, Xianjin Yin, Feng Wang, Zhuangzhuang Li, Zhenyu Zhang, Zhaolei Zheng   +6 more
doaj   +1 more source

An environmentally friendly design for low-grade diasporic-bauxite processing

, 2009
A new environmentally friendly design for low-grade diasporic-bauxite processing which is different from the Bayer and sintering processes was proposed in this paper.
Ma, Shu-hua, Wen, Zong-guo, Ma, SH, Zheng, Shi-li, Chen, Ji-ning   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Study on Fluidization Characteristics of Pulse-Type Hood in Circulating Fluidized Bed Boilers

发电技术
ObjectivesWhen large-scale circulating fluidized bed (CFB) boilers are involved in deep peak regulation, the fluidization quality inside the furnace deteriorates.
LIU Zhicun, WANG Quanhai, LU Xiaofeng, WANG Yingqiu, RUAN Xiongwei   +4 more
doaj   +1 more source

The use of conventional and advanced magnetic resonance techniques in the assessment of primary brain tumours [PDF]

, 2008
The aim of the work described in this thesis was to investigate the value of conventional, perfusion- and diffusion-weighted magnetic resonance imaging (MRI) in patients with histology-proven low-grade gliomas (LGG), and the potential role of these ...
Caseiras, G.D.B.
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source