Results 41 to 50 of about 1,399,259 (268)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Study on Working Fluids Testing and Multiphase Flow Model Optimization in Thermoacoustic Engines [PDF]

E3S Web of Conferences
This study investigates the impact of different working fluids on the performance of non-phasechange thermoacoustic engines and compares the application of two multiphase flow models in phasechange thermoacoustic engines. Simulation results show that, at
Xie Jiutian, Ren Fan, Yang Jiale
doaj   +1 more source

MLD–MPC for Ultra-Supercritical Circulating Fluidized Bed Boiler Unit Using Subspace Identification

Energies, 2022
Before carbon capture and storage technologies can truly be promoted and applied, and nuclear or renewable energy power generation can become predominant, it is important to further develop more efficient and ultra-low emission USC units on the basis of ...
Chen Yang, Tao Zhang, Zonglong Zhang, Li Sun   +3 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Prediction of interfacial area concentration based on interpretable neural network

He jishu
BackgroundInterfacial area concentration (IAC) is a key parameter of the interface transfer term in the closed two-fluid model of two-phase flow, which characterizes the strength of the gas-liquid interface transport capacity.
ZHOU Yuhao, XU Wangtao, LIU Li, ZHU Longxiang, ZHANG Luteng, PAN Liangming   +5 more
doaj   +1 more source

Low-Grade Osteosarcoma of the Mandible [PDF]

Journal of Maxillofacial and Oral Surgery, 2010
Osteosarcoma (OS), a rare malignant bone tumour arising from primitive bone forming mesenchyme, most often arises in the metaphyses of long bones of the extremities. Bone or osteoid formation within the tumour is characteristic of an osteosarcoma. Craniofacial osteosarcoma (CFOS), most often located in the mandible or maxilla, accounts for only 5-13 ...
Ramen, Sinha, S K, Roy Chowdhury, P K, Chattopadhyay, K, Rajkumar   +3 more
openaire   +2 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Numerical simulation on the generation characteristics of nitrogen-containing pollutants during co-gasification process of biomass and polyethylene

能源环境保护
The co-gasification of biomass and polyethylene in an updraft gasifier can effectively increase the calorific value of the syngas and the H2 yield. However, the generation and emission characteristics of nitrogen-containing pollutants during the co ...
Chuanchang XU, Suhan LUO, Xianqing ZHU, Jun LI, Xun ZHU, Qiang LIAO   +5 more
doaj   +1 more source