Results 241 to 250 of about 7,356,032 (313)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Study on the measurement and driving mechanisms for coordinated development level of digital economy and low-carbon economy: evidence from China. [PDF]

Carbon Balance Manag
Zhou D, Song Y.
europepmc   +1 more source

ICT for Low Environmental Impact (Sustainable) Development

Material Cycles and Waste Management Research, 2013
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Exploring the potential impact of medical errors research on population health. [PDF]

PLoS One
Sarquis Rivera MA, Hernandez-Paez DA, Galván-Barrios J, Barceló-Martinez E, Narvaez-Rojas AR, Lozada-Martinez ID.   +5 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Coupling coordination between ecological environment quality and public health of residents in the Yellow River Basin, China: A modified coupling coordination model approach. [PDF]

PLoS One
Zhao J, Xie Q, Liu Y.
europepmc   +1 more source

Ex Ante Life Cycle Assessment of Industrial-Scale Electrochemical Reduction of CO₂ to Formic Acid. [PDF]

ACS Sustain Chem Eng
Nickel L, Schuler E, Rawls B, van den Bosch B, Stahl K, Moser P, Shen L.   +6 more
europepmc   +1 more source

Has the development of artificial intelligence promoted urban pollutant and carbon emission reduction? Evidence from China. [PDF]

Front Public Health
Li M, Liu T, Wu G, Lin J, Guo B.
europepmc   +1 more source