Results 31 to 40 of about 131,516 (230)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

On low topics in Najdi Arabic: a rejoinder to Alshamari and Jarrah (2022)

open access: yesLinguistics
In this article empirical evidence is presented against the existence of a discourse-laden low IP in Najdi Arabic as proposed by Alshamari, Murdhy & Marwan Jarrah. (2022. The fine structure of low topics in Najdi Arabic. Linguistics 60(4). 1011–1038). In
Alzayid Ali
doaj   +1 more source

SCHC over LoRaWAN Efficiency: Evaluation and Experimental Performance of Packet Fragmentation

open access: yesSensors, 2022
Low Power Wide Area Networks (LPWAN) are expected to enable the massive connectivity of small and constrained devices to the Internet of Things. Due to the restricted nature of both end devices and network links, LPWAN technologies employ network stacks ...
Rodrigo Muñoz   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Final results of production test IP-348-I, K area low-flow calibration test [PDF]

open access: yes, 1961
K area emergency water backup studies have been hampered by poor data on flow through the reactor under various emergency conditions. Various tests have been run where emergency conditions have been simulated and flow measurements attempted. In all previous tests, the accuracy of the flow measurements have been questionable. Flow from the high-pressure
openaire   +2 more sources

Cold atmospheric argon plasma jet source and its application for bacterial inactivation

open access: yesJournal of Theoretical and Applied Physics, 2019
In this work, the efficiency of inactivation of a cold argon plasma jet at atmospheric pressure (APPJ) on the basis of a low-current spark discharge into microorganisms with different characteristics of the cell walls was evaluated.
Bair B. Baldanov   +3 more
doaj   +1 more source

Do climate teleconnections modulate wildfire-prone conditions over the Iberian Peninsula?

open access: yesEnvironmental Research Letters, 2021
Climate teleconnections (CT) synchronize and influence weather features such as temperature, precipitation and, subsequently, drought and fuel moisture in many regions across the globe.
Marcos Rodrigues   +4 more
doaj   +1 more source

Integration of ERT, IP and SP Methods in Hard Rock Engineering

open access: yesApplied Sciences, 2021
Investigation of a hard rock site for the development of engineered structures mainly depends on the delineation of weathered and unweathered rock, and the fractures/faults. Traditionally, borehole tests are used in such investigations.
Peng Shao   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Security and Vulnerability of SCADA Systems over IP-Based Wireless Sensor Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2012
An overview of supervisory control and data acquisition (SCADA) systems is presented and relevant security concerns are addressed. To secure IP-based SCADA systems, it is vital to implement secure architectures which prevent access to the SCADA from ...
HyungJun Kim
doaj   +1 more source

Home - About - Disclaimer - Privacy