Results 121 to 130 of about 3,184,733 (264)

A Low-Loss 1.2 kV SiC MOSFET with Improved UIS Performance. [PDF]

Micromachines (Basel), 2023
Wu L, Zhang M, Liang J, Liu M, Zhang T, Yang G.   +5 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Multiport Programmable Silicon Photonics Using Low-Loss Phase Change Material Sb₂Se₃. [PDF]

Nano Lett
Radford TW, Rozaqi L, Ajia IA, Deoli P, Yan X, Banakar M, Thomson DJ, Zeimpekis I, Politi A, Muskens OL.   +9 more
europepmc   +1 more source

Hollow-core pear-shaped conjoined-tube fiber with low loss in the ultraviolet band. [PDF]

Heliyon, 2023
Cheng Y, Pan Y, Liu H, Xiao Y, Deng S, Teng C, Yang H, Deng H, Yuan L.   +8 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Spatially-Controlled Planar Guided Crystallization of Low-Loss Phase Change Materials for Programmable Photonics. [PDF]

Adv Mater
Bentata F, Taute A, Laprais C, Orobtchouk R, Kempf E, Gassenq A, Pipon Y, Calvo M, Martinez V, Monfray S, Saint-Girons G, Baboux N, Nguyen HS, Letartre X, Berguiga L, Genevet P, Cueff S.   +16 more
europepmc   +1 more source

A low-loss molybdenum plasmonic waveguide: perfect single-crystal preparation and subwavelength grating optimization. [PDF]

Nanophotonics, 2023
Cui T, Shen Y, Cheng A, Zhan R, Zheng Z, Tian B, Shi J, Ke Y, Shao L, Chen H, Deng S.   +10 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Design of a Low-Loss microstrip Lowpass-Bandpass triplexer with closely spaced channels for modern RF communication systems. [PDF]

Sci Rep
Yahya SI, Zubir F, Nouri L, Jizat NM.
europepmc   +1 more source