Results 131 to 140 of about 3,184,733 (264)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Low-loss silicon nitride Kerr-microresonators fabricated with metallic etch masks via metal lift-off. [PDF]

Sci Rep
Colación GM, Rukh L, Buck FH, Drake TE.
europepmc   +1 more source

Design of 2 μm Low-Loss Hollow-Core Anti-Resonant Fibers. [PDF]

Micromachines (Basel), 2023
Sun T, Su X, Su X, Meng F, Wang Z, Song J, Zhang C, Xu T, Zhang Y, Zhang H, Cui M, Zheng Y.   +11 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Low Insertion Loss Plasmon-Enhanced Graphene All-Optical Modulator

ACS Omega, 2021
Mohammed AlAloul, Mahmoud Rasras
doaj   +1 more source

Tunable Strong Plasmon-Exciton Coupling in a Low-Loss Nanocuboid Dimer with Monolayer WS₂. [PDF]

Nanomaterials (Basel)
Wu F, Chen Z.
europepmc   +1 more source

Low-loss skimming waveguides with controllable mode leakage for on-chip saturable absorbers. [PDF]

Nanophotonics, 2023
Yang Y, Zhong L, Cui Y, Wang Y, Chen D, Lau KY, Liu X, Ma Z, Barillaro G, Chen Z, Qiu J.   +10 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Low-Carbohydrate Diet is More Helpful for Weight Loss Than Low-Fat Diet in Adolescents with Overweight and Obesity: A Systematic Review and Meta-Analysis

Diabetes, Metabolic Syndrome and Obesity
Yu Zhang,1– 4 Tingting He,1– 4 Yu Hu,1– 4 Chenlin Gao2– 5 1Graduate School, Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Cardiovascular and Metabolic Diseases Key Laboratory of Luzhou, Affiliated Hospital of Southwest ...
Zhang Y, He T, Hu Y, Gao C
doaj  

High-responsivity InSe/TaSe₂ photodetectors integrated on low-loss silicon nitride waveguides. [PDF]

Nanoscale Adv
Qureshi MA, Khalid F, Uddin MG, Shafi AM, Doughan I, Tippinit J, Ahmed F, Cui X, Roussey M, Lipsanen H, Sun Z, Kuittinen M.   +11 more
europepmc   +1 more source