Results 171 to 180 of about 8,090,991 (304)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Tunable Strong Plasmon-Exciton Coupling in a Low-Loss Nanocuboid Dimer with Monolayer WS₂. [PDF]

Nanomaterials (Basel)
Wu F, Chen Z.
europepmc   +1 more source

Low-loss skimming waveguides with controllable mode leakage for on-chip saturable absorbers. [PDF]

Nanophotonics, 2023
Yang Y, Zhong L, Cui Y, Wang Y, Chen D, Lau KY, Liu X, Ma Z, Barillaro G, Chen Z, Qiu J.   +10 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

High-responsivity InSe/TaSe₂ photodetectors integrated on low-loss silicon nitride waveguides. [PDF]

Nanoscale Adv
Qureshi MA, Khalid F, Uddin MG, Shafi AM, Doughan I, Tippinit J, Ahmed F, Cui X, Roussey M, Lipsanen H, Sun Z, Kuittinen M.   +11 more
europepmc   +1 more source

Low-loss MIMO antenna wireless communication system for 5G cardiac pacemakers. [PDF]

Sci Rep, 2023
Sharma D, Kanaujia BK, Kumar S, Rambabu K, Matekovits L.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Creation of Low-Loss Triple-Ring Optical Filter via Direct Binary Search Inverse Design. [PDF]

Sensors (Basel)
Hu Y, Wang T, Zhou W, Hu B.
europepmc   +1 more source

Library of single-etch silicon nitride grating couplers for low-loss and fabrication-robust fiber-chip interconnection. [PDF]

Sci Rep, 2023
Korček R, Medina Quiroz D, Wilmart Q, Edmond S, Cheben P, Vivien L, Alonso-Ramos C, Benedikovič D.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source