Results 121 to 130 of about 6,573,875 (320)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

The Kraft Break Sharply Divides Low-mass and Intermediate-mass Stars

The Astrophysical Journal
Main-sequence stars transition at mid-F spectral types from slowly rotating (cooler stars) to rapidly rotating (hotter stars), a transition known as the Kraft Break and attributed to the disappearance of the outer convective envelope, causing magnetic ...
Alexa C. Beyer, Russel J. White
doaj   +1 more source

Projectile - Mass asymmetry systematics for low energy incomplete fusion

EPJ Web of Conferences, 2015
In the present work, low energy incomplete fusion (ICF) in which only a part of projectile fuses with target nucleus has been investigated in terms of various entrance channel parameters.
Singh Pushpendra P., Yadav Abhishek, Sharma Vijay R., Sharma Manoj K., Kumar Pawan, Sahoo Rudra N., Kumar R., Singh R. P., Muralithar S., Singh B. P., Bhowmik R. K., Prasad R.   +11 more
doaj   +1 more source

Common envelope binary interaction simulations between a thermally pulsating AGB star and a low mass companion. [PDF]

Mon Not R Astron Soc, 2022
González-Bolívar M, De Marco O, Lau MYM, Hirai R, Price DJ.   +4 more
europepmc   +1 more source

Mass Spectrometry of Substances of Low Volatility [PDF]

, 1958
H. W. Holden, J. C. Robb
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Imaging low-mass planets within the habitable zone of α Centauri. [PDF]

Nat Commun, 2021
Wagner K, Boehle A, Pathak P, Kasper M, Arsenault R, Jakob G, Käufl U, Leveratto S, Maire AL, Pantin E, Siebenmorgen R, Zins G, Absil O, Ageorges N, Apai D, Carlotti A, Choquet É, Delacroix C, Dohlen K, Duhoux P, Forsberg P, Fuenteseca E, Gutruf S, Guyon O, Huby E, Kampf D, Karlsson M, Kervella P, Kirchbauer JP, Klupar P, Kolb J, Mawet D, N'Diaye M, Orban de Xivry G, Quanz SP, Reutlinger A, Ruane G, Riquelme M, Soenke C, Sterzik M, Vigan A, de Zeeuw T.   +41 more
europepmc   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

OGLE-2017-BLG-0448Lb: A Low Mass–Ratio Wide-orbit Microlensing Planet?

The Astronomical Journal
The gravitational microlensing technique is most sensitive to planets in a Jupiter-like orbit and has detected more than 200 planets. However, only a few wide-orbit ( s > 2) microlensing planets have been discovered, where s is the planet-to-host ...
Ruocheng Zhai, Radosław Poleski, Weicheng Zang, Youn Kil Jung, Andrzej Udalski, Renkun Kuang, Leading Authors, Michael D. Albrow, Sun-Ju Chung, Andrew Gould, Cheongho Han, Kyu-Ha Hwang, Yoon-Hyun Ryu, In-Gu Shin, Yossi Shvartzvald, Hongjing Yang, Jennifer C. Yee, Sang-Mok Cha, Dong-Jin Kim, Hyoun-Woo Kim, Seung-Lee Kim, Chung-Uk Lee, Dong-Joo Lee, Yongseok Lee, Byeong-Gon Park, Richard W. Pogge, The KMTNet Collaboration, Jan Skowron, Michał K. Szymański, Igor Soszyński, Krzysztof Ulaczyk, Paweł Pietrukowicz, Szymon Kozłowski, Przemek Mróz, Krzysztof A. Rybicki, Patryk Iwanek, Marcin Wrona, Mariusz Gromadzki, The OGLE Collaboration, Hanyue Wang, Shude Mao, Jiyuan Zhang, Qiyue Qian, Wei Zhu, The MAP Collaboration   +44 more
doaj   +1 more source

Searches for Low Mass Higgs Boson at the Tevatron

EPJ Web of Conferences, 2012
We present the result of the searches for a low mass Standard Model Higgs boson performed at the Tevatron pp¯ $par p$ collider (√s = 1.96 TeV) by the CDF and D0 experiments with an integrated luminosity of up to 8.5 fb-1.
Sforza Federico
doaj   +1 more source