Results 131 to 140 of about 16,047,641 (362)

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

LEO P: AN UNQUENCHED VERY LOW-MASS GALAXY [PDF]

, 2015
Leo P is a low-luminosity dwarf galaxy discovered through the blind H i Arecibo Legacy Fast ALFA survey. The H i and follow-up optical observations have shown that Leo P is a gas-rich dwarf galaxy with active star formation, an underlying older ...
K. McQuinn, E. Skillman, A. Dolphin, J. Cannon, J. Salzer, K. Rhode, E. Adams, D. Berg, R. Giovanelli, L. Girardi, M. Haynes   +10 more
semanticscholar   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

The clinical eficacy of vitamin D in children with primary low bone mass [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2011
Introduction: Vitamin D suplementation in prevention and treatment of osteoporosis is a widely accepted standard, but the latest studies show the necessity of increasing the intake of this vitamin to keep its concetration on higher levels ?
Danuta Chlebna-Sokół, Jolanta Karalus
doaj  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Study of Mg–Al–Ca magnesium alloy ameliorated with designed Al8Mn4Gd phase

Journal of Magnesium and Alloys, 2020
To investigate the effect of Al8Mn4Gd phase on microstructural and mechanical properties of Mg–Al–Ca magnesium alloy, two Mg–2.5Al2Ca and Mg–2.5Al2Ca-0.1Al8Mn4Gd alloys were designed and compared in this work.
Chaosheng Ma, Wenbo Yu, Xufeng Pi, Antoine Guitton   +3 more
doaj  

Low-mass black holes as the remnants of primordial black hole formation [PDF]

, 2012
This article documents our ongoing search for the elusive "intermediate-mass" black holes. These would bridge the gap between the approximately ten solar mass "stellar-mass" black holes that are the end-product of the life of a massive star, and the "supermassive" black holes with masses of millions to billions of solar masses found at the centers of ...
arxiv   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Health disparities and climate change in the Marshall Islands

Annals of Medicine
The small island nations, territories, and states dotting the Pacific are among the most disproportionately affected populations worldwide in the face of climate change.
Kathryn J. Pollard, Cory Davis, Brenda Davis, David Donohue, William Wong, Ali Saad, Gia Merlo, Neha Pathak   +7 more
doaj   +1 more source

Ultraviolet emission lines in young low-mass galaxies at z ≃ 2: physical properties and implications for studies at z > 7 [PDF]

, 2014
We present deep spectroscopy of 17 very low mass (M* similar or equal to 2.0 x 10(6)-1.4 x 10(9) M-circle dot) and low luminosity (M-UV similar or equal to -13.7 to -19.9) gravitationally lensed ga ...
D. Stark, J. Richard, B. Siana, S. Charlot, W. Freeman, Julia Gutkin, A. Wofford, B. Robertson, R. Amanullah, D. Watson, B. Milvang-Jensen   +10 more
semanticscholar   +1 more source