Results 71 to 80 of about 16,812,166 (316)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Low muscle mass, low muscle function, and sarcopenia in the urban and rural elderly

open access: yesScientific Reports, 2022
Health outcomes of the elderly vary between rural and urban areas. Sarcopenia is diagnosed as loss of muscle strength or impaired physical performance, namely “low muscle function” and low muscle mass.
Sung Woo Moon   +6 more
doaj   +1 more source

The M-dwarfs in Multiples (MinMs) survey – I. Stellar multiplicity among low-mass stars within 15 pc [PDF]

open access: yes, 2015
We present a large-scale, volume-limited companion survey of 245 late-K to mid-M (K7-M6) dwarfs within 15 pc. Infrared adaptive optics (AO) data were analysed from the Very Large Telescope, Subaru Telescope, Canada-France-Hawaii Telescope, and MMT ...
K. Ward-Duong   +10 more
semanticscholar   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

The Coronal Temperatures of Low-Mass Main-Sequence Stars [PDF]

open access: yes, 2015
Aims. We study the X-ray emission of low-mass main-sequence stars to derive a reliable general scaling law between coronal temperature and the level of X-ray activity. Methods.
C. Johnstone, M. Gudel
semanticscholar   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Low fat ratio is better riskfFactor than low body mass index for low bone mineral density

open access: yesMedicine Science, 2017
Osteoporosis is a health problem that limits quality life and may cause morbidity and mortality, unless prevented or actively treated. The objective of the study was to determine the effects of risk factors on bone mineral density. We evaluated 353 women
Fatih Bati
doaj   +1 more source

A STUDY IN BLUE: THE BARYON CONTENT OF ISOLATED LOW-MASS GALAXIES [PDF]

open access: yes, 2015
We study the baryon content of low-mass galaxies selected from the Sloan Digital Sky Survey (SDSS DR8), focusing on galaxies in isolated environments where the complicating physics of galaxy–galaxy interactions are minimized. We measure neutral hydrogen (
J. Bradford, M. Geha, M. Blanton
semanticscholar   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

A model of strain hardening for stage IV based on lattice curvature induced dislocations and grain fragmentation

open access: yesJournal of Materials Research and Technology
A new model is presented for the interpretation of the nearly linear Stage IV large strain hardening behavior observed in polycrystalline metals.
Laszlo S. Toth, Anthony D. Rollett
doaj   +1 more source

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