Results 91 to 100 of about 10,209,746 (308)

Effects on spatial skills after exposure to low frequency noise

open access: yes, 2004
A study of spatial skills was conducted with 27 male and 27 female participants. The aim of the study was to examine the post-exposure effect of a complex low frequency noise (21 Hz) on a mental rotation task.
Neely, Gregory   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Spatial Smoothing for Diffusion Tensor Imaging with low Signal to Noise Ratios [PDF]

open access: yes, 2003
Though low signal to noise ratio (SNR) experiments in DTI give key information about tracking and anisotropy, e.g. by measurements with very small voxel sizes, due to the complicated impact of thermal noise such experiments are up to now seldom analysed.
Prigarin, Sergej M.   +4 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Ultralow-Noise Chopper Amplifier for Seafloor E-Field Measurement

open access: yesSensors
The seafloor E-field signal is extremely weak and difficult to measured, even with a high signal-to-noise ratio. The preamplifier for electrodes is a key technology for ocean-bottom electromagnetic receivers.
Sixuan Song, Kai Chen
doaj   +1 more source

Life-cycle costs and infrastructural investments induced by unconventional low-noise aircraft

open access: yes, 2015
The environment challenge and the expected growth of the market demand impose a technology breakthrough within the aeronautical industry. Although several innovative configurations of airplanes have been analyzed, none of them has been yet chosen as the ...
CENTRACCHIO, FRANCESCO   +2 more
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Low-Noise 3-D Avalanche Photodiodes

open access: yesIEEE Photonics Journal, 2016
In this paper, we present a new 3-D structure for the InP-based avalanche photodiode, aiming at decreasing the excess noise factor. To the best of our knowledge, it is the first time new device designs based on the recently developed 3-D spatial dead ...
Zhiwei Wu   +3 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

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