Results 81 to 90 of about 10,209,746 (308)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Design of CMOS Charge-sensitive Amplifier for Coaxial High Purity Germanium Detector
Yuanzineng kexue jishuHigh purity germanium detectors play an increasingly significant role in particle physics and astrophysics, particularly in low-background radiation measurement experiments, due to their exceptional energy resolution, high detection efficiency.
LIU Zhan, HE Gaokui, LIU Haifeng
doaj +1 more source
Free Space Optic Receiver with Strongly Overlapped Photodetectors’ Field of View
Applied Sciences, 2019 In this study, we designed a mobile free space optic receiver that uses several photodetectors to provide omnidirectional receiving capability. Assuming only one transmitter, it is a receiver which builds a single input multiple output optical channel ...
Karel Witas, Jan Nedoma
doaj +1 more source
Process Implementation for the System Evaluation of new Low-Noise STOL Transportation Concepts [PDF]
, 2009 The German Aerospace Center (DLR) has initiated the project Quiet Short Take-Off and Landing (QSTOL) to set up a multidisciplinary analysis process for new low-noise STOL transportation concepts.
Schneider, Oliver +4 more
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Low noise pavement characterization through TCN analysis
The use of low-noise pavements is a valid solution to reduce road traffic noise at source. Further studies are needed to optimize their design and ensure their durability.
MORO, Antonino +4 more
core +1 more source
Low-frequency noise impact on CMOS image sensors [PDF]
, 2009 CMOS image sensors are nowadays extensively used in imaging applications even for high-end applications. This is really possible thanks to a reduction of noise obtained, among others, by Correlated Double Sampling (CDS) readout.
Magnan, Pierre +1 more
core
Are the comfort classes noise and vibration levels on board really suitable?
, 2021 In shipbuilding industry, comfort is a relevant issue both for crew members and passengers. A comfortable environment enables crew members to perform accurately their tasks and it is an effective factor contributing to the satisfaction of passengers ...
Flavia D'Agostin +2 more
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Numerical modeling of InGaAs/AlGaAs heterostructure for short-wave infrared nBn photodetectors
Journal of the European Optical Society-Rapid PublicationsnBn infrared photodetectors have emerged as a strong alternative to conventional pn and pin-based structures due to their low dark current, fast response, and suppression of Shockley–Read–Hall (SRH) generation pathways. In this study, an InP-based InGaAs/
Tok Çağrı +5 more
doaj +1 more source