Results 71 to 80 of about 2,736,349 (294)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Free Space Optic Receiver with Strongly Overlapped Photodetectors’ Field of View

open access: yesApplied Sciences, 2019
In this study, we designed a mobile free space optic receiver that uses several photodetectors to provide omnidirectional receiving capability. Assuming only one transmitter, it is a receiver which builds a single input multiple output optical channel ...
Karel Witas, Jan Nedoma
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Design of CMOS Charge-sensitive Amplifier for Coaxial High Purity Germanium Detector

open access: yesYuanzineng kexue jishu
High purity germanium detectors play an increasingly significant role in particle physics and astrophysics, particularly in low-background radiation measurement experiments, due to their exceptional energy resolution, high detection efficiency.
LIU Zhan, HE Gaokui, LIU Haifeng
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A correlation noise spectrometer for flicker noise measurement in graphene samples [PDF]

open access: yes, 2019
We present a high-resolution digital correlation spectrum analyzer for the measurement of low frequency resistance fluctuations in graphene samples. The system exploits the cross-correlation method to reject the amplifiers' noise.
Callegaro, Luca   +3 more
core   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Doubled Full Shot Noise in Quantum Coherent Superconductor - Semiconductor Junctions

open access: yes, 2003
We performed low temperature shot noise measurements in Superconductor (TiN) - strongly disordered normal metal (heavily doped Si) weakly transparent junctions. We show that the conductance has a maximum due to coherent multiple reflections at low energy
C. Hoffmann   +4 more
core   +1 more source

Matched wideband low-noise amplifiers for radio astronomy [PDF]

open access: yes, 2009
Two packaged low noise amplifiers for the 0.3–4 GHz frequency range are described. The amplifiers can be operated at temperatures of 300–4 K and achieve noise temperatures in the 5 K range (
Bardin, J.   +3 more
core   +1 more source

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