Results 81 to 90 of about 484,819 (300)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A Finite Block Length Achievability Bound for Low Probability of Detection Communication [PDF]
2018 International Symposium on Information Theory and Its Applications (ISITA), 2018 Low probability of detection (or covert) communication refers to the scenario where information must be sent reliably to a receiver, but with low probability of detection by an adversary. Recent works on the fundamental limits of this communication problem have established achievability and converse bounds that are asymptotic in the block length of the
openaire +2 more sources
Optimal features for online seizure detection [PDF]
, 2012 31/07/12 MEB. accepted version attached, publisher allows this to be added.This study identifies characteristic features in scalp EEG that simultaneously give the best discrimination between epileptic seizures and background EEG in minimally pre-processed
Casson, Alexander J.; id_orcid +5 more
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Low Probability of Detection Communication Using Noncoherent Grassmannian Signaling
2025 59th Asilomar Conference on Signals, Systems, and Computers5 pages, 6 figures ...
Diego Cuevas +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Spectrogram Track Detection: An Active Contour Algorithm [PDF]
, 2010 In many areas of science, near-periodic phenomena represent important information within time-series data. This thesis takes the example of the detection of non-transitory frequency components in passive sonar data, a problem which finds many ...
Lampert, Thomas
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
A new mark-recapture approach for abundance estimation of social species.
PLoS ONE, 2018 Accurate estimates of population abundance are a critical component of species conservation efforts in order to monitor the potential recovery of populations.
Jena R Hickey, Rahel Sollmann
doaj +1 more source