Results 11 to 20 of about 11,043,311 (307)

The Pathophysiological effects of adjuvant preoperative chemotherapy and/or radiotherapy on patients with advanced rectal cancer [PDF]

, 2013
Introduction The modern treatment of colorectal cancer consists of surgery, with or without adjuvant pre-operative radiotherapy, chemotherapy or chemoradiotherapy (APT) for selected cases. In the United Kingdom, therapy may be given prior to surgery in
Rahmani, Samir
core   +6 more sources

Comparison of transanal versus laparoscopic total mesorectal excision in low rectal cancer [PDF]

Iranian Journal of Colorectal Research, 2020
Background: Transanal Total Mesorectal Excision (TaTME) presented in recent years as a novel technique to achieve better outcome in circumferential margin (CRM) and distal margin (DRM) in lower rectal cancer operation.
Seyed Vahid Hosseini, Leila Ghahramani, Seyed Farhad Tayari, Alireza Izadi, Razieh Sadat Mousavi-Roknabadi, Zahra Beizavi   +5 more
doaj   +1 more source

Accuracy of High Resolution Multidetector Computed Tomography in the Local Staging of Rectal Cancer

Journal of Gastrointestinal and Abdominal Radiology, 2022
Background Magnetic resonance imaging (MRI) is the gold standard for local staging of rectal cancer. Advanced computed tomography (CT) machines are now capable of high-resolution images of rectal cancer and utilized for CT perfusion.
Rochita Venkata Ramanan, Venkatesh Munikrishnan, Akash Venkataramanan, Sudeepta Kumar Swain, Kaveripattu Sathiyamurthy Sunilkumar, Vadanika Venu, Muthuswamy Hariharan, Mohammad Zehran Saipillai, Asfar Ahamed   +8 more
doaj   +1 more source

Anastomotic leak after minimally invasive anterior resection for rectal cancer with high versus low ligation of the inferior mesenteric artery: a study protocol for a multicentre randomized clinical trial

Trials, 2022
Background Although many efforts have been made to decrease the incidence of anastomotic leak (AL), it remains one of the most serious complications of rectal cancer surgery.
Soo Young Lee, Sohyun Kim, Gyung Mo Son, Hye Jin Kim, Soo Yeun Park, Jun Seok Park, Chang Hyun Kim, Gi Won Ha, Kyung-Ha Lee, Jin Soo Kim, Ki Beom Bae, Sung Uk Bae, Sung Il Kang, Korean ColoRectal surgeOn Study group of the Southern province (K-CROSS)   +13 more
doaj   +1 more source

Prognostic Implication of the m6A RNA Methylation Regulators in Rectal Cancer

Frontiers in Genetics, 2021
N6-methyladenosine (m6A) is a very common and abundant RNA modifications occurring in nearly all types of RNAs. Although the dysregulated expression of m6A regulators is implicated in cancer progression, our understanding of the prognostic value of the ...
Yajie Chen, Yajie Chen, Shanshan Wang, Shanshan Wang, William C. Cho, Xiang Zhou, Xiang Zhou, Xiang Zhou, Zhen Zhang, Zhen Zhang   +9 more
doaj   +1 more source

Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer - Preliminary results [PDF]

, 2003
Background: The local recurrence rate of colorectal cancer has been significantly reduced due to the use of combined radiochemotherapy. Despite this improvement regarding locally advanced tumour recurrences, the treatment strategy for pre-treated ...
Schaffer, P.M., Ertl-Wagner, Birgit, M. Schaffer, E. Dühmke, P.M. Schaffer, R.D. Issels, Pachmann, S., Abdel-Rahman, Sultan, S. Abdel-Rahman, Abdel-Rahman, S., Ertl-Wagner, B., Krych, M., Issels, Rolf-Dieter, Dühmke, E., B. Ertl-Wagner, Schaffer, Pamela Manuela, M. Krych, S. Pachmann, Schäffer, M., Issels, R.D., Dühmke, Eckhart, Schaffer, Moshe   +21 more
core   +1 more source

Total Neoadjuvant Therapy for Rectal Cancer in the CAO/ARO/AIO-12 Randomized Phase 2 Trial: Early Surrogate Endpoints Revisited

, 2022
SIMPLE SUMMARY: Multimodal treatment of rectal cancer is undergoing dynamic change. In phase II/III multimodal rectal cancer trials, long-term survival remains the most objective endpoint for reporting treatment efficacy, but long follow-up is required ...
Diefenhardt, Markus, Simon Kirste, Michael Ghadimi, Piso, Pompiliu, Ralf-Dieter Hofheinz, Bechstein, Wolf Otto, Wolf O. Bechstein, Hildebrandt, Guido, Guido Hildebrandt, Ghadimi, Michael B., Bechstein, Wolf O., Kirste, Simon, Pompiliu Piso, Kuhnt, Thomas, Hofheinz, Ralf-Dieter, Rödel, Claus, Ghadimi, Michael, Thomas Kuhnt, Claus Rödel, Fokas, Emmanouil, Anke Schlenska-Lange, Emmanouil Fokas, Markus Diefenhardt, Schlenska-Lange, Anke   +23 more
core   +1 more source

Surgical strategy for low rectal cancers

Journal of Visceral Surgery, 2015
The two goals of surgery for lower rectal cancer surgery are to obtain clear "curative" margins and to limit post-surgical functional disorders. The question of whether or not to preserve the anal sphincter lies at the center of the therapeutic choice.
F, Dumont, A, Mariani, D, Elias, D, Goéré   +3 more
openaire   +2 more sources

Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity [PDF]

, 2002
Background: The standard therapy for patients with clinically resectable rectal cancer is generally considered to be surgery, If the patient is diagnosed with advanced disease, postoperative radiochemotherapy (RCT) is usually recommended. In our study we
Wilkowski, R., Schaffer, Pamela Manuela, Thoma, M., Dühmke, Eckhart, Schaffer, Moshe   +4 more
core   +1 more source

The Safety and Feasibility of Laparoscopic Surgery for Very Low Rectal Cancer: A Retrospective Analysis Based on a Single Center’s Experience

Biomedicines, 2021
In this work we intend to validate the long-term oncologic outcomes for very low rectal cancer over the past 20 years and to determine whether laparoscopic procedures are useful options for very low rectal cancer.
Hyuk-Jun Chung, Jun-Gi Kim, Hyung-Jin Kim, Hyeon-Min Cho, Bong-Hyeon Kye   +4 more
doaj   +1 more source