Impact of Neoadjuvant Approach and Tumor Response on Survival in Pancreatic Adenocarcinoma
ABSTRACT Introduction Neoadjuvant therapy for pancreatic adenocarcinoma (PDAC) has evolved from single‐agent to multi‐agent approaches, largely informed by metastatic disease studies demonstrating improved survival; albeit at the price of increased toxicity. It remains unclear how response to varied neoadjuvant regimens impact survival. We hypothesized
Mohammed O. Suraju +9 more
wiley +1 more source
Case Report: Ultrasound features of pathological complete response in middle and low rectal cancer with high microsatellite instability after neoadjuvant immunotherapy: a case series. [PDF]
Liang L +5 more
europepmc +1 more source
ABSTRACT Objective To assess how diagnostic pathways affect clinical outcomes and healthcare costs among older adults diagnosed with colorectal cancer (CRC). Summary of Background Data Many CRC cases in the United State are diagnosed during an emergency presentation, which have been linked to worse outcomes.
Eshetu B. Worku +3 more
wiley +1 more source
Transanal versus robotic total mesorectal excision for mid- and low-rectal cancer: A single-center comparative cohort of 109 patients. [PDF]
Lin CL +8 more
europepmc +1 more source
Factors Associated With Receipt of Adjuvant Radiation in Locally Advanced Rectal Cancer
ABSTRACT Background Neoadjuvant radiotherapy (RT) has been the standard of care for locally advanced rectal cancer (LARC) for over two decades. Adjuvant RT use in LARC represents a deviation from standard care and warrants further investigation. Objectives To identify factors associated with adjuvant RT utilization.
Maryam Sherwani +4 more
wiley +1 more source
Quality of life after laparoscopic surgery for very low rectal cancer: A sub-analysis of the ultimate trial. [PDF]
Hamamoto H +27 more
europepmc +1 more source
ABSTRACT Background and Objectives Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is established for peritoneal surface malignancies, but its use in older patients is debated. We assessed CRS‐HIPEC morbidity and mortality in patients aged ≥ 70 years using a cohort of younger patients as a comparator.
Ali Ediz Kıvanç +4 more
wiley +1 more source
A preoperative MRI pelvic multiparameter nomogram for predicting sphincter preservation and operative difficulty in laparoscopic total mesorectal excision for ultra-low rectal cancer. [PDF]
Jin H, Zhang Q, Feng L, Ying R, Ju H.
europepmc +1 more source
ABSTRACT Background and Methods The role of early and increased activity on postoperative recovery is well established, yet the impact of its day‐to‐day variability remains unclear. This retrospective cohort study examined associations between early in‐hospital postoperative physical activity trajectories and postoperative outcomes among 218 surgical ...
Ella Jansen +4 more
wiley +1 more source
Effects of preoperative CALLY index and intraoperative LCA preservation on postoperative complications and LARS following robot-assisted mid and low rectal cancer surgery: a retrospective study. [PDF]
Wu H +11 more
europepmc +1 more source

