ABSTRACT Response to neoadjuvant chemoradiotherapy (NACRT) in locally advanced colorectal cancer (CRC) varies widely, and accurately identifying poor responders is crucial for guiding timely treatment modification. This study aimed to develop an integrated predictive model combining radiomics derived from routine radiotherapy non‐contrast planning ...
Sin‐Hua Moi +6 more
wiley +1 more source
Early-stage low rectal cancer - re-thinking the standard of care. [PDF]
Bunjo Z, Sammour T.
europepmc +1 more source
Effectiveness of intraoperative stay sutures and postoperative anal dilatation in preventing anastomotic stricture after low rectal cancer resection with defunctioning stoma. [PDF]
Wei D +7 more
europepmc +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Machine learning combined with body composition predicts surgical difficulty in mid-low rectal cancer surgery. [PDF]
Li X +7 more
europepmc +1 more source
ABSTRACT The Global Burden of Disease (GBD) database provides essential primary data for public health research. However, its complexity and diversity pose challenges for conducting advanced secondary analyses. To address these challenges, we developed easyGBDR, an innovative integrated R toolkit designed to facilitate the secondary analysis of GBD ...
Yingying Fang +9 more
wiley +1 more source
Reducing Low Anterior Resection Syndrome After Low Rectal Cancer Surgery Using an Integrated Intra-Anal Balloon Training and Reminder Device: Feasibility Nonrandomized Controlled Trial. [PDF]
Zhang Q +7 more
europepmc +1 more source
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong +7 more
wiley +1 more source
Comparison analysis of short-term outcomes between degradable stent placement and diverting ileostomy in mid-to-low rectal cancer: a retrospective cohort study. [PDF]
Wen J +5 more
europepmc +1 more source
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei +4 more
wiley +1 more source

