Results 31 to 40 of about 106,309 (217)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Meridional distribution and seasonal variation of stable oxygen isotope ratio of precipitation in the Southern Ocean

open access: yesAntarctic Record, 2010
The stable oxygen isotope ratio(δ^O) in precipitation is known to have important meridional and seasonal variations, but there are almost no measurements of δ^O in precipitation over polar oceans.
Kayo Nakamura   +3 more
doaj   +1 more source

Genomic Characteristics of Desulfonema ishimotonii Tokyo 01T Implying Horizontal Gene Transfer Among Phylogenetically Dispersed Filamentous Gliding Bacteria

open access: yesFrontiers in Microbiology, 2019
Desulfonema ishimotonii strain Tokyo 01T is a filamentous sulfate-reducing bacterium isolated from a marine sediment. In this study, the genome of this strain was sequenced and analyzed with a focus on gene transfer from phylogenetically distant ...
Miho Watanabe   +4 more
doaj   +1 more source

A CONSTANT TEMPERATURE BATH FOR LOW TEMPERATURES. [PDF]

open access: yesJournal of the American Chemical Society, 1905
n ...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A compound-specific method for measuring the stable carbon isotopic composition of amino acids: elimination of the effect of isotopic fractionation during derivatization

open access: yesProgress in Earth and Planetary Science
Compound-specific isotope analysis (CSIA) of carbon and nitrogen within amino acids by gas chromatography/isotope ratio mass spectrometry (GC/IRMS) has been employed as a powerful tool for estimating the trophic tendency and resource utilization of ...
Yoshito Chikaraishi   +3 more
doaj   +1 more source

Unconventional fractional quantum Hall states and Wigner crystallization in suspended Corbino graphene

open access: yesNature Communications, 2018
Understanding of ordered phases of interacting electrons in 2D systems is a fundamental many-body physics problem. Here, the authors report unconventional fractional quantum Hall phases in graphene Corbino devices originating from residual interactions ...
Manohar Kumar   +2 more
doaj   +1 more source

Enhanced expression of genes in the brains of larvae of Mamestra brassicae (Lepidoptera: Noctuidae) exposed to short daylength or fed Dopa

open access: yesEuropean Journal of Entomology, 2003
The cabbage armyworm, Mamestra brassicae, enters diapause in the early pupal stage. Pupal diapause is induced by rearing the larvae under short day lengths.
Masahide URYU   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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