Results 41 to 50 of about 3,354,892 (317)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Meridional distribution and seasonal variation of stable oxygen isotope ratio of precipitation in the Southern Ocean

Antarctic Record, 2010
The stable oxygen isotope ratio(δ^O) in precipitation is known to have important meridional and seasonal variations, but there are almost no measurements of δ^O in precipitation over polar oceans.
Kayo Nakamura, Shigeru Aoki, Takenobu Toyota, Yuichi Aoyama   +3 more
doaj   +1 more source

Genomic Characteristics of Desulfonema ishimotonii Tokyo 01T Implying Horizontal Gene Transfer Among Phylogenetically Dispersed Filamentous Gliding Bacteria

Frontiers in Microbiology, 2019
Desulfonema ishimotonii strain Tokyo 01T is a filamentous sulfate-reducing bacterium isolated from a marine sediment. In this study, the genome of this strain was sequenced and analyzed with a focus on gene transfer from phylogenetically distant ...
Miho Watanabe, Miho Watanabe, Hisaya Kojima, Kazuhiro Umezawa, Manabu Fukui   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A compound-specific method for measuring the stable carbon isotopic composition of amino acids: elimination of the effect of isotopic fractionation during derivatization

Progress in Earth and Planetary Science
Compound-specific isotope analysis (CSIA) of carbon and nitrogen within amino acids by gas chromatography/isotope ratio mass spectrometry (GC/IRMS) has been employed as a powerful tool for estimating the trophic tendency and resource utilization of ...
Yoshito Chikaraishi, Hyuntae Choi, Nayeon Park, Yuko Takizawa   +3 more
doaj   +1 more source

Enhanced expression of genes in the brains of larvae of Mamestra brassicae (Lepidoptera: Noctuidae) exposed to short daylength or fed Dopa

European Journal of Entomology, 2003
The cabbage armyworm, Mamestra brassicae, enters diapause in the early pupal stage. Pupal diapause is induced by rearing the larvae under short day lengths.
Masahide URYU, Yohsuke NINOMIYA, Takeshi YOKOI, Seiji TSUZUKI, Yoichi HAYAKAWA   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Continuous time crystal coupled to a mechanical mode as a cavity-optomechanics-like platform

Nature Communications
Time crystals are an enigmatic phase of matter in which a quantum mechanical system displays repetitive, observable motion – they spontaneously break the time translation symmetry.
J. T. Mäkinen, P. J. Heikkinen, S. Autti, V. V. Zavjalov, V. B. Eltsov   +4 more
doaj   +1 more source

Unconventional fractional quantum Hall states and Wigner crystallization in suspended Corbino graphene

Nature Communications, 2018
Understanding of ordered phases of interacting electrons in 2D systems is a fundamental many-body physics problem. Here, the authors report unconventional fractional quantum Hall phases in graphene Corbino devices originating from residual interactions ...
Manohar Kumar, Antti Laitinen, Pertti Hakonen   +2 more
doaj   +1 more source