Results 61 to 70 of about 16,460,279 (279)

Negative lift generation in a tidal device structure [PDF]

open access: yes, 2009
Becoming aware of the impact of global warming, all countries of the European Union have agreed to produce 20% of their electricity from renewable energy by 2020.
Thilleul, Olivia
core   +3 more sources

Driving pressure is not associated with mortality in mechanically ventilated patients without ARDS

open access: yesCritical Care, 2019
Background In patients with acute respiratory distress syndrome (ARDS), low tidal volume ventilation has been associated with reduced mortality. Driving pressure (tidal volume normalized to respiratory system compliance) may be an even stronger predictor
Michael J. Lanspa   +9 more
doaj   +1 more source

Efeitos de diferentes volumes correntes e da pressão expiratória final positiva sobre a troca gasosa na fístula broncopleural experimental Effects of different tidal volumes and positive end expiratory pressure on gas exchange in experimental bronchopleural fistula

open access: yesRevista Brasileira de Terapia Intensiva, 2008
OBJETIVO: O presente estudo foi desenhado para identificar o efeito da pressão expiratória final positiva (PEEP) e o volume corrente pulmonar ideal para ventilar animais com fístula broncopleural produzida cirurgicamente, com o intuito de reduzir a vazão
Maria Gabriela Cavicchia Toneloto   +4 more
doaj   +1 more source

Validation of a tool for estimating clinician recognition of ARDS using data from the international LUNG SAFE study.

open access: yesPLOS Digital Health, 2023
Under-recognition of acute respiratory distress syndrome (ARDS) by clinicians is an important barrier to adoption of evidence-based practices such as low tidal volume ventilation. The burden created by the COVID-19 pandemic makes it even more critical to
Meagan A Bechel   +7 more
doaj   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang   +14 more
wiley   +1 more source

New approach to tidal stream energy analysis at sites in the English Channel

open access: yes, 2009
Tidal stream power generation offers the prospect of predictable, low-CO2power at a number of locations around the UK and the world. Previousassessments of tidal energy resources have taken the form of desk studiesbased on simplified navigational data ...
Blunden, L.S.
core   +1 more source

The Effects of Airway Pressure Release Ventilation on Pulmonary Permeability in Severe Acute Respiratory Distress Syndrome Pig Models

open access: yesFrontiers in Physiology, 2022
Objective: The aim of the study was to compare the effects of APRV and LTV ventilation on pulmonary permeability in severe ARDS.Methods: Mini Bama adult pigs were randomized into the APRV group (n = 5) and LTV group (n = 5).
Jiangli Cheng   +8 more
doaj   +1 more source

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin   +10 more
wiley   +1 more source

Modelling tidal energy extraction in a depth-averaged coastal domain [PDF]

open access: yes, 2010
An extension of actuator disc theory is used to describe the properties of a tidal energy device, or row of tidal energy devices, within a depth-averaged numerical model This approach allows a direct link to be made between an actual tidal device and its
M.L.G. Oldfield   +7 more
core   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

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