Results 91 to 100 of about 501,759 (281)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Nanopore Fabrication by Controlled Dielectric Breakdown

open access: yes, 2013
Nanofabrication techniques for achieving dimensional control at the nanometer scale are generally equipment-intensive and time-consuming. The use of energetic beams of electrons or ions has placed the fabrication of nanopores in thin solid-state ...
Briggs, Kyle   +2 more
core   +3 more sources

Pineapples internal quality inspection approaches and its potential effects in Malaysia [PDF]

open access: yes, 2020
Pineapple (Ananas Comosus L. Metil) is a tropical plant under Bromeliaceous family that is grown in American tropics, subtropics, and warmer regions (U. Nations 2012). Pineapple is the second harvest tropical fruit after banana in the world (S.
Jam, Mohamad Nur Hakim   +2 more
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Hysteretic current-voltage characteristics and resistance switching at a rectifying Ti/Pr$_{0.7}$Ca$_{0.3}$MnO$_{3}$ interface

open access: yes, 2004
We have characterized the vertical transport properties of epitaxial layered structures composed of Pr$_{0.7}$Ca$_{0.3}$MnO$_{3}$ (PCMO) sandwiched between SrRuO$_{3}$ (SRO) bottom electrode and several kinds of top electrodes such as SRO, Pt, Au, Ag ...
Fujii, T.   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Stacked Symmetrical Non-Isolated High Step-Up Voltage Gain Converter with High Efficiency and Low Voltage Stress on Components

open access: yesEnergies
This paper introduces a cascaded symmetrical non-isolated high step-up voltage gain converter with high efficiency and low voltage stress on components combining a non-isolated buck-boost converter and voltage doubler structure. In the proposed converter,
Minh-Chau Dinh, Thi-Tinh Le, Minwon Park
doaj   +1 more source

Comparison between flying capacitor and modular multilevel inverter [PDF]

open access: yes, 2009
The paper describes the operational principle of flying capacitor and modular multilevel inverters. The detailed discussions of dc link capacitors voltage balancing methods for both inverters are given in order to enable fair comparison. The causes of dc
Adam, G.P.   +5 more
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Hybrid and Three-Level Three-Phase Rectifiers Using Interleaved DCM Boost Converters

open access: yesIEEE Access, 2019
Two new three-phase high-power-factor rectifiers using an interleaved discontinuous conduction mode (DCM) boost converters in a three-level configuration are proposed in this paper. The input currents waveforms follow the input voltages waveforms without
Marcelo Henrique Granza   +2 more
doaj   +1 more source

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