Results 121 to 130 of about 186,890 (303)
High voltage gain switched z‐source inverter with low current stress
IET Power ElectronicsThis paper proposes a switched Z‐source inverter with high voltage gain and low current stress on elements. Also, a new switching method corresponding to the proposed topology is introduced.
Golaleh Zarei +4 more
doaj +1 more source
Space Charge Behaviour at LDPE Interface under AC Electric Stress
, 2006 This paper reports on measurements of space charge characteristics in single and two-layer of low-density polyethylene (LDPE) films subjected to an applied voltage with a range of frequencies from dc to 50 Hz.
Xu, Z, Chen, G
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
An Interleaved Low Switch Voltage Stress Boost Converter for Power Factor Correction
, 2012 [[abstract]]In this paper, a two-phase interleaved boost converter with low switch voltage stress and automatic current-sharing capability is proposed for single-phase power factor correction (PFC).
Cing-Tsai Pan;C. M. Lai;Y. L. Juan;L. T. Hsu
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Partial Discharge Inception Voltage Monitoring of Enameled Wires under Thermal Stress over Time
Electrical insulation is a critical component in electrical machines. The performance of the insulation system can be adversely affected by operating conditions that induce aging. Assessing the impact of environmental stresses is essential for predicting
Torello, Eugenia +7 more
core +1 more source
Temperature effect on space charge dynamics in XLPE insulation
, 2007 This paper reports on space charge evolution in crosslinked polyethylene (XLPE) planar samples approximately 1.20 mm thick subjected to electric stress level of 30 kVdc/mm under four temperature 25 oC, 50 oC, 70 oC and 90 oC for 24 hours.
Y.l. Chong +7 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source