Results 71 to 80 of about 499,765 (280)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A non‐isolated DC‐DC converter with low voltage stress and high step‐down voltage conversion ratio

IET Power Electronics, 2021
This work focuses on a new non‐isolated interleaved DC‐DC converter with very high step‐down voltage conversion ratio. By employing the switched/series capacitor concept, along with the proper component interconnection, the converter features a high step‐
Stylianos P. Syrigos, Georgios C. Christidis, Theodoros P. Mouselinos, Emmanuel C. Tatakis   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Transmission electron microscopy and x-ray diffraction investigation of the microstructure of nanoscale multilayer TiAlN/VN grown by unbalanced magnetron deposition [PDF]

, 2005
Cubic NaCl-B1 structured multilayer TiAlN/VN with a bi-layer thickness of approximately 3 nm and atomic ratios of (Ti+Al)/V = 0.98 to 1.15 and Ti/V = 0.55 to 0.61 were deposited by unbalanced magnetron sputtering at substrate bias voltages between -75 ...
Chu, D.B. Lewis, Geist, P.Eh. Hovsepian, Q. Luo, W-D. Münz   +5 more
core   +1 more source

Triple-Voltage Gain and Self-Balancing in a New Switched-Capacitor Seven-Level Inverter for Microgrid Integration

Energies
In the context of power electronic interfaces in photovoltaic (PV), fuel cell, battery, and microgrid applications, the low output voltage of the DC source necessitates a voltage-boosting inverter. This paper proposes a single-source seven-level switched-
Mohamed Salem, Mahmood Swadi, Anna Richelli, Yevgeniy Muralev, Faisal A. Mohamed   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Analysis of a Bidirectional DC-DC Converter with High Voltage Gain [PDF]

, 2015
A novel bidirectional DC-DC converter with high conversion ratio is proposed in this paper. The proposed converter uses the three windings coupled-inductor to achieved high voltage conversion ratio.
Razzaghzadeh, B. (Behrouz), Salimi, M. (Mahdi)   +1 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Area-Delay-Energy Tradeoffs of Strain-Mediated Multiferroic Devices

, 2015
Multiferroic devices hold profound promise for ultra-low energy computing in beyond Moore's law era. The magnetization of a magnetostrictive shape-anisotropic single-domain nanomagnet strain-coupled with a piezoelectric layer in a multiferroic composite ...
Roy, Kuntal
core   +1 more source