Results 61 to 70 of about 13,257,834 (322)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

A Nearly Tight Sum-of-Squares Lower Bound for the Planted Clique Problem [PDF]

IEEE Annual Symposium on Foundations of Computer Science, 2016
We prove that with high probability over the choice of a random graph G from the Erdös-Rényi distribution G(n,1/2), the nO(d)-time degree d Sum-of-Squares semidefinite programming relaxation for the clique problem will give a value of at least n1/2-c(d/
B. Barak, Samuel B. Hopkins, Jonathan A. Kelner, Pravesh Kothari, Ankur Moitra, Aaron Potechin   +5 more
semanticscholar   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Randomized complexity lower bounds [PDF]

Proceedings of the thirtieth annual ACM symposium on Theory of computing - STOC '98, 1998
The complexity lower bound (log N) is proved for randomized computation trees (over reals with branching signs f ; >g) for recognizing an arrangement or a polyhedron with N faces. A similar lower bound is proved for randomized computation trees over any zero-characteristic eld with branching signs f=; 6 =g for recognizing an arrangement.
openaire   +2 more sources

Symmetry Parameter Constraints from a Lower Bound on Neutron-matter Energy [PDF]

, 2016
We propose the existence of a lower bound on the energy of pure neutron matter (PNM) on the basis of unitary-gas considerations. We discuss its justification from experimental studies of cold atoms as well as from theoretical studies of neutron matter ...
I. Tews, J. Lattimer, A. Ohnishi, E. Kolomeitsev   +3 more
semanticscholar   +1 more source

Cramer-Rao Lower Bound and Information Geometry

, 2013
This article focuses on an important piece of work of the world renowned Indian statistician, Calyampudi Radhakrishna Rao. In 1945, C. R. Rao (25 years old then) published a pathbreaking paper, which had a profound impact on subsequent statistical ...
Nielsen, Frank
core   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

Lower Bounds of Copson Type for Hausdorff Matrices on Weighted Sequence Spaces [PDF]

Journal of Sciences, Islamic Republic of Iran, 2011
Let = be a non-negative matrix. Denote by the supremum of those , satisfying the following inequality: where , , and also is increasing, non-negative sequence of real numbers.
R. Lashkaripour
doaj  

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source