Results 81 to 90 of about 6,618,541 (298)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A lower bound for approximating grundy numbering
Discrete Mathematics & Theoretical Computer Science, 2007 The grundy numbering of a graph is the maximum number of colors used by on-line first-fit coloring, under the worst order of arrival of vertices. The grundy numbering problem is to find this ordering.
Guy Kortsarz
doaj
New results for generalized Hausdorff matrices
Journal of Inequalities and ApplicationsLet A = ( a n , k ) n , k ≥ 0 $A=(a_{n,k})_{n,k\geq 0}$ be a non-negative matrix. Denote by L p ( A ) $L_{p}(A)$ , the supremum of those ℓ, satisfying the following inequality ( ∑ n = 0 ∞ ( ∑ k = 0 ∞ a n , k x k ) p ) 1 p ≥ ℓ ( ∑ k = 0 ∞ x k p ) 1 p ( x ≥
Gholamreza Talebi
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Journal of Topology, 2018 We prove a new lower bound for the dilatation of an arbitrary pseudo-Anosov map on a surface of genus g with n punctures. Our bound improves the former super-exponential dependence on the genus by a polynomial dependence.
openaire +5 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Fractal and FractionalIn order to achieve time–frequency superresolution in comparison to the conventional Wigner distribution (WD), this study generalizes the well-known τ-Wigner distribution (τ-WD) with only one parameter τ to the multiple-parameter matrix-Wigner ...
Long Wang +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source