Results 101 to 110 of about 6,618,541 (298)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Lower Bound for the Class Number of ℚn2+4
International Journal of Mathematics and Mathematical Sciences, 2020 In this paper, we give an explicit lower bound for the class number of real quadratic field ℚd, where d=n2+4 is a square-free integer, using ωn which is the number of odd prime divisors of n.
Hasan Sankari, Ahmad Issa
doaj +1 more source
Lower bounds for kernelizations
Electron. Colloquium Comput. Complex., 2007 "Vegeu el resum a l'inici del document del fitxer adjunt".
Yijia Chen 0001 +2 more
openaire +2 more sources
Lower bounds on paraclique density
Discrete Applied Mathematics, 2016 The scientific literature teems with clique-centric clustering strategies. In this paper we analyze one such method, the paraclique algorithm. Paraclique has found practical utility in a variety of application domains, and has been successfully employed to reduce the effects of noise.
Ronald D. Hagan +2 more
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Optimal monetary and fiscal policy with a zero bound on nominal interest rates [PDF]
, 2012 I characterize optimal monetary and fiscal policy in a stochastic New Keynesian model when nominal interest rates may occasionally hit the zero lower bound.
Schmidt, Sebastian
core
A Lower Bound Analysis of Hamming Distortion for a Binary CEO Problem with Joint Source-Channel Coding [PDF]
, 2015 A two-node binary chief executive officer (CEO) problem is investigated. Noise-corrupted versions of a binary sequence are forwarded by two nodes to a single destination node over orthogonal additive white Gaussian noise (AWGN) channels.
Matsumoto, Tad +4 more
core +1 more source
Lyapunov-type inequalities for nonlinear systems involving the (p1,p2,...,pn)-Laplacian
Electronic Journal of Differential Equations, 2013 We prove some generalized Lyapunov-type inequalities for n-dimensional Dirichlet nonlinear systems.
Devrim Cakmak +2 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source