Results 121 to 130 of about 13,257,834 (322)

A Shadow Rate Model with Time-Varying Lower Bound of Interest Rates

open access: yesSocial Science Research Network, 2016
Typically a constant – or zero – lower bound for interest rates is applied in shadow rate term structure models. However, euro area yield curve data suggest that a time-varying lower bound might be appropriate for the euro area.
Tomi Kortela
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Distance Lower Bounding [PDF]

open access: yes, 2015
Distance upper-bounding DUB allows a verifier to know whether a proving party is located within a certain distance bound. DUB protocols have many applications in secure authentication and location based services. We consider the dual problem of distance lower bounding DLB, where the prover proves it is outside a distance bound to the verifier.
Xifan Zheng   +2 more
openaire   +1 more source

The Risky Steady State and the Interest Rate Lower Bound

open access: yesSocial Science Research Network, 2016
Even when the policy rate is currently not constrained by its effective lower bound (ELB), the possibility that the policy rate will become constrained in the future lowers today's inflation by creating tail risk in future inflation and thus reducing ...
Timothy S. Hills   +2 more
semanticscholar   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

α-Nearness Ant Colony System with Adaptive Strategies and Performance Analysis

open access: yesCybernetics and Information Technologies, 2015
This paper proposes an improved ant colony system with adaptive strategies, called ...
Lv Jinqiu, You Xiaoming, Liu Sheng
doaj   +1 more source

Lower Bound for the Class Number of ℚn2+4

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2020
In this paper, we give an explicit lower bound for the class number of real quadratic field ℚd, where d=n2+4 is a square-free integer, using  ωn which is the number of odd prime divisors of n.
Hasan Sankari, Ahmad Issa
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Home - About - Disclaimer - Privacy