Results 181 to 190 of about 5,110,730 (289)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Lower bounds on trees and unicyclic graphs with respect to the misbalance rodeg index. [PDF]
HeliyonDehgardi N, Azari M, Shang Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Recent lower bounds for geometric-arithmetic index [PDF]
Discrete Mathematics Letters, 2019 Ana Portilla +2 more
doaj
Subexponential lower bounds for <i>f</i>-ergodic Markov processes. [PDF]
Probab Theory Relat FieldsBrešar M, Mijatović A.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Two New Families of Local Asymptotically Minimax Lower Bounds in Parameter Estimation. [PDF]
Entropy (Basel)Merhav N.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
An investigation on the use of copulas when calculating general cash flow distributions. [PDF]
In a paper of 2000, Kaas, Dhaene and Goovaerts investigate the present value of a rather general cash flow as a special case of sums of dependent risks.
Darkiewicz, Grzegorz +4 more
core
Tight Lower Bounds for Directed Cut Sparsification and Distributed Min-Cut. [PDF]
Proc ACM Manag DataCheng Y +5 more
europepmc +1 more source