Results 91 to 100 of about 8,204 (174)

Thermisch kontrollierter chiraler supramolekularer Polymorphismus in Wasser

Angewandte Chemie, EarlyView.
Unter Verwendung eines amphiphilen Oligophenylenethinylen Derivats haben wir LCST‐gekoppelte Chiralität als Strategie zur Regulierung von thermoresponsivem supramolekularem Polymorphismus in Wasser etabliert. Bei Raumtemperatur bildet AggI diskrete Ansammlungen, die in der Nähe des LCST in elongierte helikale Fasern (AggII) übergehen und schlussendlich
Zulema Fernández, Yongsheng Li, Daniel Martínez, Julia Terlau, Myongsoo Lee, Bartolomé Soberats, Gustavo Fernández   +6 more
wiley   +1 more source

Thermally Controlled Chiral Supramolecular Polymorphism in Water

Angewandte Chemie International Edition, EarlyView.
Using an amphiphilic oligo(phenyleneethynylene) derivative, we establish LCST‐coupled chirality as a strategy to regulate thermoresponsive supramolecular polymorphism in water. At room temperature, AggI forms discrete assemblies that transform into elongated helical fibers (AggII) near the LCST and subsequently to sheet‐like structures (AggIII) at ...
Zulema Fernández, Yongsheng Li, Daniel Martínez, Julia Terlau, Myongsoo Lee, Bartolomé Soberats, Gustavo Fernández   +6 more
wiley   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Understanding cationic polyelectrolyte thermogels with varying charge densities toward biomaterials design

BMEMat, EarlyView.
Cationic polyurethane thermogels with customizable charge density were developed, exhibiting enhanced pH‐responsiveness. This work elucidates how cationic charges influence self‐assembly and thermogelling, providing insights for designing smart biomaterials.
Belynn Sim, Yi Jing Wong, Hamzah Kamaruddin, Qianyu Lin, Pablo Mota‐Santiago, Nigel Kirby, Alexis Lee, Yihao Leow, Alice Anhan Chen, Rubayn Goh, Xian Jun Loh   +10 more
wiley   +1 more source

Hybrid biofunctional nanostructures as stimuli-responsive catalytic systems

Beilstein Journal of Organic Chemistry, 2010
A novel active biocatalytic reaction system is proposed by covalently immobilizing porcine pancreas trypsin within the thermoresponsive polymer shell of superparamagnetic Fe3O4 nanoparticles.Active ester-functional nanocarriers suitable for the ...
Gernot U. Marten, Thorsten Gelbrich, Annette M. Schmidt   +2 more
doaj   +1 more source

On the Molecular Origin of the Cooperative Coil-to-globule Transition of Poly(N-isopropylacrylamide) in Water

, 2018
By means of atomistic molecular dynamics simulations we investigate the behaviour of poly(N-isopropylacrylamide), PNIPAM, in water at temperatures below and above the lower critical solution temperature (LCST), including the undercooled regime.
Chiessi, E., Tavagnacco, L., Zaccarelli, E.   +2 more
core   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

BMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu, Baoqin Song, Zhihao Chen, Wenzhong Li, Wanjun Liang, Xiu Wang   +5 more
wiley   +1 more source

Self‐Immolative Gels: Programmable Degradation Using Self‐Immolative Linkers and Polymers

Chemistry – A European Journal, EarlyView.
Self‐immolative linkers and polymers undergo bond‐cleaving reaction cascades in response to specific stimuli. Their incorporation into gels can be harnessed to release cargo, induce property changes, or trigger degradation in a highly controlled manner. These functions can be employed in applications such as sensing and drug delivery.
Chuanfeng Li, Elizabeth R. Gillies
wiley   +1 more source

Inter‐Verified Binary Classification Models: Unveiling Key Polymer Features Against Staphylococcus aureus

Carbon Innovation, EarlyView.
ABSTRACT Antimicrobial peptides (AMPs) are promising alternatives to antibiotics but require precise and costly sequence control for efficacy. Synthetic polymers composed of acrylate and acrylamide offer a simpler and more time‐efficient antibacterial strategy compared to AMPs.
Jooyoung Roh, Cyrille Boyer, Priyank Kumar   +2 more
wiley   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang, Viktoria Lahmann, Jan Philipp Bittner, Pablo Domínguez de María, Sven Jakobtorweihen, Irina Smirnova, Selin Kara   +6 more
wiley   +1 more source