Results 51 to 60 of about 365,329 (283)

Two-Year Follow-Up Shows Gentamicin-Coated Tibial Nails Reduce Infection Rates in Open Tibial Fractures

Antibiotics
Introduction: Open tibial fractures carry a high risk of fracture-related infection (FRI), and prevention typically relies on early antibiotics and debridement. However, achieving optimum local antibiotic concentration remains challenging.
Álvaro I. Zamorano, Matías A. Vaccia, Carlos F. Albarrán, Rodrigo I. Parra, Tomás Turner, Ignacio A. Rivera, Tomás Errázuriz, Andrés Oyarzún, Osvaldo A. Garrido, Pablo F. Suárez, Pierluca Zecchetto, Luis A. Bahamonde   +11 more
doaj   +1 more source

Frictional alopecia of the distal legs: case series and review [PDF]

, 2016
BackgroundAcquired alopecia of the lower legs may occur secondary to friction due to socks, footwear, or both on the lower extremities. There is scant literature that reports on this phenomenon.Methods and MaterialsWe describe 5 patients who presented ...
Cohen, Philip R, Zhao, Johnny
core   +2 more sources

Survey of the needs of patients with spinal cord injury: impact and priority for improvement in hand function in tetraplegics\ud [PDF]

, 2004
Objective: To investigate the impact of upper extremity deficit in subjects with tetraplegia.\ud \ud Setting: The United Kingdom and The Netherlands.\ud \ud Study design: Survey among the members of the Dutch and UK Spinal Cord Injury (SCI) Associations.\
BR Johnstone, C Long, C Murphy, CL Mc Dowell, E Moberg, EG Widerstrom-Noga, EM Andresen, G Bedbrook, GJ Snoek, GW Torrance, JF Ditunno, JH van Tuijl, L Harvey, LA Harvey, LA May, M Curtin, M Dijkers, M Johannesson, M Ryan, MJ De Vivo, MW Keith, MW Keith, P Kersten, PH Gorman, PH Peckham, R Triolo, R Waters, RF Pangalila, RJ Cox, RM Andersen, RW Hanson   +30 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Factors predicting failure of internal fixations of fractures of the lower limbs: a prospective cohort study

BMC Musculoskeletal Disorders, 2021
Background We assessed predictive factors of patients with fractures of the lower extremities caused by trauma. We examined which factors are associated with an increased risk of failure.
Barbara Prediger, Thorsten Tjardes, Christian Probst, Anahieta Heu-Parvaresch, Angelina Glatt, Dominique Rodil dos Anjos, Bertil Bouillon, Tim Mathes   +7 more
doaj   +1 more source

Compliant walker [PDF]

, 1992
A compliant walker is provided for humans having limited use of their legs and lower back. It includes an upright wheel frame which at least partially surrounds an upright user wearing a partial body harness. It is attached to the frame by means of cable
Crane, J. Allen, Eklund, Wayne D., Kerley, James J.   +2 more
core   +1 more source

Differential contractile response of critically ill patients to neuromuscular electrical stimulation [PDF]

, 2019
BACKGROUND: Neuromuscular electrical stimulation (NMES) has been investigated as a preventative measure for intensive care unit-acquired weakness. Trial results remain contradictory and therefore inconclusive.
Carbon, Niklas M., Goll, Moritz, Grunow, Julius J., Liebl, Max E., Weber-Carstens, Steffen, Wollersheim, Tobias   +5 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Asimetría de extremidades inferiores: Evaluación por imágenes en la edad pediátrica

Revista Chilena de Radiología
La asimetría de extremidades inferiores o anisomelia ha sido largamente objetivada con imágenes y posee implicancias biomecánicas para los pacientes con esqueleto en desarrollo que son más relevantes que los aspectos cosméticos, tanto en su tratamiento ...
Samuel Sánchez C, Ximena Ortega F, Alejandro Baar A, Susana Lillo S, Alejandro De la Maza B, Karla Moenne B, Juan A Escaffi J, Carolina Pérez S   +7 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source