Results 81 to 90 of about 7,490,775 (397)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Losing a Limb, Regaining Independence: A Systematic Review of Occupational Therapy Interventions for Lower Extremity Amputations [PDF]
, 2016 Primary Focus: Rehab, Disability & Participation Learning Objectives: Describe lower extremity residual limb care interventions within the scope of occupational therapy Explain the prevalence of individuals who sustain a lower extremity amputation and
Berzins, OTS, Davis +4 more
core +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Are clinical measures of foot posture and mobility associated with foot kinematics when walking?
Journal of Foot and Ankle Research, 2015 Background There is uncertainty as to which foot posture measures are the most valid in terms of predicting kinematics of the foot. The aim of this study was to investigate the associations of clinical measures of static foot posture and mobility with ...
Andrew K. Buldt +5 more
doaj +1 more source
ISCHAEMIA IN THE NEONATE–CASE REPORT
Angiologia e Cirurgia Vascular, 2018 Introduction: Peripheral ischaemia and gangrene in a neonate is rare,with fewer than a hundred cases reported in the literature. Neonatal limb ischaemia present considerable challenges in diagnosis and management.
Roger Rodrigues +9 more
doaj +1 more source
A Rehabilitation Engineering Course for Biomedical Engineers [PDF]
, 2002 This paper describes an upper division elective course in rehabilitation engineering that addresses prosthetics and orthotics, wheelchair design, seating and positioning, and automobile modifications for individuals with disabilities.
Silver-Thorn, M. Barbara
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Kinematic Differences between Land and Shallow-water Sprinting [PDF]
, 2015 Previous studies have demonstrated the efficacy of using aquatic-based (AB) running when compared to land-based (LB) running to produce similar gains.
Huth, Laurel, Schmidt, Ellie
core +1 more source
Impact of Lower Extremity Artery Patency and Comorbidities on Success of Syme Ankle Disarticulation [PDF]
, 2022 Abigail K. Loiacono +4 more
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source