Results 41 to 50 of about 788 (151)

Ferritinophagy Is Involved in the Advanced Glycation End Products‐Induced Ferroptosis of Vascular Endothelial Cells in Diabetes Mellitus

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT This study investigated the role of advanced glycation end products (AGEs) and ferritinophagy‐dependent ferroptosis in the pathogenesis of diabetic atherosclerosis obliterans. We investigated the effects of AGEs on ferroptosis and ferritinophagy in HUVECs.
Yi Huang, Yongzhi Jin, Junsheng Hu, Mengfan Li, Ming Tian, Guang Zeng, Rong Huang   +6 more
wiley   +1 more source

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

Aging Cell, Volume 24, Issue 8, August 2025.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda, Yosuke Inaba, Yuki Shiko, Yoshihito Ozawa, Vilhelm A. Bohr, Yoshiro Maezawa, Koutaro Yokote   +15 more
wiley   +1 more source

Analysing referral patterns from a primary dermatological clinic to other medical institutions for further care: A survey on patients with certain skin diseases in Japan

JEADV Clinical Practice, Volume 4, Issue 1, Page 181-187, March 2025.
Abstract Background Various skin diseases exist; some require specialist treatment. Consequently, patients with these conditions are often referred from primary dermatological clinics to other medical institutions for further secondary or tertiary care.
Daisuke Ueo, Takashi Sakai, Erika Ochiai, Jun Sese, Yutaka Hatano   +4 more
wiley   +1 more source

Diabetes and mortality risk in patients undergoing coronary angiography: The KARDIO study

Catheterization and Cardiovascular Interventions, Volume 104, Issue 4, Page 743-750, October 1, 2024.
Abstract Background Diabetes is an established risk factor for adverse cardiovascular outcomes including mortality, but the relationship between diabetes and mortality risk in the presence of the extensive or diffuse form of coronary artery disease (CAD) is controversial. Aims We evaluated the association between diabetes and mortality risk in patients
Jari A. Laukkanen, Setor K. Kunutsor, Jaakko Immonen, Jussi Hernesniemi, Juha Karvanen, Markku Eskola, KARDIO study group   +6 more
wiley   +1 more source

Deletion of endothelial IGFBP5 protects against ischaemic hindlimb injury by promoting angiogenesis

Clinical and Translational Medicine, Volume 14, Issue 6, June 2024.
1. IGFBP5 expression is elevated in ischaemic limb or hypoxic endothelial cells. 2. Deletion of IGFBP5 in the endothelium inhibits the deterioration of ischaemia‐induced limb salvage and blood perfusion. 3. IGFBP5 negatively regulates tube formation, cell proliferation and cell migration by blocking IGF signalling via phosphorylation of the IGF1R/Akt ...
Fei Song, Yu Hu, Yi‐Xiang Hong, Hu Sun, Yue Han, Yi‐Jie Mao, Wei‐Yin Wu, Gang Li, Yan Wang   +8 more
wiley   +1 more source

Study on the Correlation and Diagnostic Value of Multiple Inflammatory and Oxidative Stress Indices in Lower Extremity Arteriosclerotic Obliteration [PDF]

Zhongguo quanke yixue
Background Lower extremity arteriosclerotic obliteration (ASO) is a chronic disease characterized by the formation of atherosclerotic plaques in the lower extremity arteries, leading to arterial stenosis, occlusion, and subsequently chronic ischemia of ...
LIU Rong, LI Guoxin, LI Yunze, LIANG Lizhe, LU Fei, DANG Shijing, WU Hongjiang, LIU Xiaoyi
doaj   +1 more source

Transudative pleural effusion in pleuritis associated with immunoglobulin G4‐related disease diagnosed by thoracoscopy under local anaesthesia

Respirology Case Reports, Volume 12, Issue 6, June 2024.
We report a unique case of transudative pleural effusion associated with IgG4‐related disease in an 80‐year‐old man with multiple comorbidities. Despite initial treatment with diuretics, the effusion persisted, prompting further investigation. Medical thoracoscopy revealed lymphatic follicle hyperplasia and an abundance of IgG4‐positive plasmacytoid ...
Yuto Kato, Kentaro Fukunaga, Aya Ooka, Shunichi Tokuoka, Yoko Kataoka, Takuya Fujita, Hiroyuki Sugihara, Masafumi Yamaguchi   +7 more
wiley   +1 more source

Association between nutritional status and gait performance in Alzheimer's disease

CNS Neuroscience &Therapeutics, Volume 30, Issue 4, April 2024.
Alzheimer's disease (AD) patients in the dementia stage had worse nutritional status and gait performance than those in the MCI stage. Poorer nutritional status was associated with poorer gait performance in AD patients. Abstract Aims This study aimed to comprehensively explore the nutrition and gait of AD patients at different stages and the ...
Mingyue He, Tenghong Lian, Peng Guo, Yanan Zhang, Yue Huang, Jing Qi, Jinghui Li, Huiying Guan, Dongmei Luo, Zhan Liu, Weijia Zhang, Zijing Zheng, Hao Yue, Jing Li, Wenjing Zhang, Ruidan Wang, Fan Zhang, Xiaomin Wang, Wei Zhang   +18 more
wiley   +1 more source

Effect of adequate vessel preparation on 12-month primary patency rate of drug-eluting stents in patients with lower extremity arteriosclerosis obliterans

陆军军医大学学报
Objective‍　‍To investigate the impact of adequate lumen preparation on the 12-month primary patency rate of drug-eluting stents (DES) in patients with lower extremity arteriosclerosis obliterans （ASO） and to identify risk and protective factors for in ...
LIU Xiangyu, ZOU Yuchi, LI Xinyi
doaj   +1 more source

Application of traditional Chinese medicine nursing intervention in nursing care of elderly patients with lower extremity arteriosclerosis obliterans intervention

Huli yanjiu, 2017
Objective:To probe into the application effect of traditional Chinese medicine nursing intervention in nursing of elderly patients with lower extremity arteriosclerosis obliterans of interventional treatment.〖WT5HZ〗Methods:A total of 80 elderly patients ...
ZHANG Min
doaj