Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji +15 more
wiley +1 more source
Self-expanding stents and aortoiliac occlusive disease: A review of the literature [PDF]
The treatment of symptomatic aortoiliac occlusive disease has shifted from open to endovascular repair. Both short- and long-term outcomes after percutaneous angioplasty and stenting rival those after open repair and justify an endovascular-first ...
Bekken, J.A. (Joost) +3 more
core +1 more source
Abstract Background Various skin diseases exist; some require specialist treatment. Consequently, patients with these conditions are often referred from primary dermatological clinics to other medical institutions for further secondary or tertiary care.
Daisuke Ueo +4 more
wiley +1 more source
Regenerative Therapy in Peripheral Artery Disease [PDF]
Patients with peripheral artery disease (PAD) and critical limb ischemia are the main candidates for limb amputations and have a poor life expectancy. Frequently, these patients are not eligible for either surgical or percutaneous interventions aimed at ...
Antonia Germani +4 more
core +2 more sources
Progression of Vascular Disease in the Diabetic Lower Extremity [PDF]
Diabetes mellitus is a major health care issue affecting thousands of people each year. As medical research strives for a better understanding of diabetes, the life expectancy of diabetics is increasing, and the complications associated with this disease
Reinecke, Kathleen
core +1 more source
Diabetes and mortality risk in patients undergoing coronary angiography: The KARDIO study
Abstract Background Diabetes is an established risk factor for adverse cardiovascular outcomes including mortality, but the relationship between diabetes and mortality risk in the presence of the extensive or diffuse form of coronary artery disease (CAD) is controversial. Aims We evaluated the association between diabetes and mortality risk in patients
Jari A. Laukkanen +6 more
wiley +1 more source
Study on the Correlation and Diagnostic Value of Multiple Inflammatory and Oxidative Stress Indices in Lower Extremity Arteriosclerotic Obliteration [PDF]
Background Lower extremity arteriosclerotic obliteration (ASO) is a chronic disease characterized by the formation of atherosclerotic plaques in the lower extremity arteries, leading to arterial stenosis, occlusion, and subsequently chronic ischemia of ...
LIU Rong, LI Guoxin, LI Yunze, LIANG Lizhe, LU Fei, DANG Shijing, WU Hongjiang, LIU Xiaoyi
doaj +1 more source
Therapeutische Effizienz von Naftidrofuryl auf die periphere arterielle Verschlußkrankheit im Stadium II unter besonderer Berücksichtigung der transkutanen Sauerstoffpartialdruckmessung mittels Laufbandbelastung [PDF]
Eine Option zur Verbesserung der klinischen Beschwerdesymptomatik bei Patienten mit arterieller Verschlusskrankheit im Stadium II ist die Applikation vasoaktiver Substanzen. Zur Beurteilung der medikamentösen Therapieeffizienz werden die Verbesserung der
Klauck, Martina Christa +1 more
core +1 more source
Deletion of endothelial IGFBP5 protects against ischaemic hindlimb injury by promoting angiogenesis
1. IGFBP5 expression is elevated in ischaemic limb or hypoxic endothelial cells. 2. Deletion of IGFBP5 in the endothelium inhibits the deterioration of ischaemia‐induced limb salvage and blood perfusion. 3. IGFBP5 negatively regulates tube formation, cell proliferation and cell migration by blocking IGF signalling via phosphorylation of the IGF1R/Akt ...
Fei Song +8 more
wiley +1 more source
We report a unique case of transudative pleural effusion associated with IgG4‐related disease in an 80‐year‐old man with multiple comorbidities. Despite initial treatment with diuretics, the effusion persisted, prompting further investigation. Medical thoracoscopy revealed lymphatic follicle hyperplasia and an abundance of IgG4‐positive plasmacytoid ...
Yuto Kato +7 more
wiley +1 more source

