Results 121 to 130 of about 374,943 (358)

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

Effects of Modification of Pain Protocol on Incidence of Post Operative Nausea and Vomiting. [PDF]

, 2016
BackgroundA Perioperative Surgical Home (PSH) care model applies a standardized multidisciplinary approach to patient care using evidence-based medicine to modify and improve protocols.
Ahn, Kyle, Bahn, Esther, Calderon, Michael-David, Harrington, Brian, Rinehart, Joseph B, Schwarzkopf, Ran, Sharfman, Zachary T, Snir, Nimrod   +7 more
core   +2 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Timing of Colonoscopy in Acute Lower Gastrointestinal Bleeding: A Multicenter Retrospective Cohort Study.

Gastrointestinal Endoscopy, 2022
Y. Shiratori, N. Ishii, Tomonori Aoki, Katsumasa Kobayashi, A. Yamauchi, Atsuo Yamada, J. Omori, T. Aoyama, N. Tominaga, Yoshinori Sato, T. Kishino, Tsunaki Sawada, Masaki Murata, Akinari Takao, K. Mizukami, K. Kinjo, S. Fujimori, T. Uotani, M. Fujita, Hiroki Sato, Sho Suzuki, T. Narasaka, J. Hayasaka, T. Funabiki, Y. Kinjo, A. Mizuki, S. Kiyotoki, T. Mikami, Ryosuke Gushima, Hiroyuki Fujii, Y. Fuyuno, N. Gunji, Y. Toya, K. Narimatsu, N. Manabe, K. Nagaike, Tetsu Kinjo, Y. Sumida, S. Funakoshi, K. Kobayashi, T. Matsuhashi, Y. Komaki, K. Miki, Kazuhiro Watanabe, Kazuki Yamamoto, T. Yoshimoto, Ayaka Takasu, Takashi Ikeya, F. Omata, Katsuyuki Fukuda, M. Kaise, N. Nagata   +51 more
semanticscholar   +1 more source

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]

, 2016
The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico, DELLE FAVE, Gianfranco, Desideri, F, DI GIULIO, Emilio, Menasci, F, Pagnini, C   +5 more
core   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Colonoscopy in the diagnosis of acute lower gastrointestinal bleeding

Journal of Coloproctology, 2016
Lower gastrointestinal bleeding is defined as a bleeding originated from a source distal to the Treitz ligament and the colonoscopy is well established as the diagnostic procedure of choice.
Igor Borba de Souza e Benevides, Carlos Henrique Marques dos Santos   +1 more
doaj   +1 more source

Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms [PDF]

, 2018
We analyzed 597 patients with myeloproliferative neoplasms (MPN) who presented transient ischemic attacks (TIA, n = 270) or ischemic stroke (IS, n = 327). Treatment included aspirin, oral anticoagulants, and cytoreductive drugs.
Arellano-Rodrigo, Eduardo, Barbui, Tiziano, Beggiato, Eloise, Bellini, Marta, Bertozzi, Irene, Betti, Silvia, Bonifacio, Massimiliano, Cacciola, Emma, Cacciola, Rossella, Carli, Giuseppe, Carobbio, Alessandra, Cattaneo, Daniele, Cazzola, Mario, Censori, Bruno, Cervantes, Francisco, Cortelezzi, Agostino, De Stefano, Valerio, Di Lazzaro, Vincenzo, Elli, Elena Maria, Ellis, Martin H., Finazzi, Guido, Finazzi, Maria Chiara, Gaidano, Gianluca, Gomez, Montse, Griesshammer, Martin, Guglielmelli, Paola, Hernandez-Boluda, Juan-Carlos, Iurlo, Alessandra, Loscocco, Giuseppe Gaetano, Lunghi, Francesca, Miroslava, Palova, Musolino, Caterina, Palandri, Francesca, Randi, Maria Luigia, Rapezzi, Davide, Rossi, Elena, Rumi, Elisa, Sadjadian, Parvis, Scaffidi, Luigi, Tieghi, Alessia, Vannucchi, Alessandro M., Vianelli, Nicola   +41 more
core   +5 more sources

Learning Curve Effect in Reducing Local Recurrence Rate After Resection of Pancreatic Cancer With Arterial Abutment: A Single‐Center Retrospective Study

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) with arterial abutment is a complex, high‐risk surgery. We aimed to investigate the clinicopathological features, risk factors, and learning curve for local recurrence after pancreatectomy for PDAC with arterial abutment.
Jun Ishida, Hirochika Toyama, Takayuki Kodama, Yoshihide Nanno, Takuya Mizumoto, Shohei Komatsu, Hiroaki Yanagimoto, Masahiro Kido, Tomoo Ito, Takumi Fukumoto   +9 more
wiley   +1 more source