Results 101 to 110 of about 10,331,359 (299)

The biochemical and molecular characterisation of respiratory mucins in TB [PDF]

, 2006
Includes bibliographical references (leaves 96-112).The role of the dominant respiratory mucins (MUC5AC and MUC5B) and MUC2 has been investigated in chronic airway diseases as it is the mucin glycoprotein that confers upon mucus its biological ...
Govender, Ureshnie
core   +1 more source

RESULTS OF BACTERIOLOGICAL TESTS IN THOSE SUFFERING FROM PULMONARY MALICIOUS TUMORS DEPENDING ON THE PRESENCE OF COPD AND TECHNIQUE OF THE SAMPLE COLLECTION FROM THE RESPIRATORY TRACT

Туберкулез и болезни лёгких, 2016
Goal of the study: to study the bacterial population in the respiratory tract at various levels in those suffering from pulmonary malicious tumors including patients with concurrent chronic obstructive pulmonary disease (COPD).Materials and methods ...
A. N. Zhakot, D. V. Sokolov, S. D. Mitrokhin, V. V. Shevtsov, V. V. Sokolov, B. S. Lenskiy   +5 more
doaj   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Value of Chest Radiographic Pattern in RSV Disease of the Newborn: A Multicenter Retrospective Cohort Study

Critical Care Research and Practice, 2012
Respiratory syncytial virus (RSV) lower respiratory tract infection is the most common viral respiratory infection in infants. Several authors have sought to determine which risk factors are the best predictors for severe RSV disease.
Américo Gonçalves, Gustavo Rocha, Hercília Guimarães, Paula Cristina Fernandes, Elisa Proença, Dulce Oliveira, Paula Rocha, Conceição Quintas, Teresa Martins, Alice Freitas, Clara Paz Dias, Albina Ramires   +11 more
doaj   +1 more source

Covalently Linked Peptides and Membrane Potential Enable CyaA Segment Translocation

Advanced Science, EarlyView.
Using a newly developed Droplet Interface Bilayer‐Pipette assay, the authors show that two segments of the CyaA toxin cross membranes by distinct mechanisms. One segment translocates spontaneously, whereas the translocation of the other depends on membrane potential.
Gaia Scilironi, Nicolas Carvalho, Jacinthe Frangieh, Corentin Léger, Dorothée Raoux‐Barbot, J. Iñaki Guijarro, Daniel Ladant, Sophie Cribier, Nicolas Rodriguez, Alexandre Chenal   +9 more
wiley   +1 more source

ApoA1, ApoB, ApoA1/B for Pathogenic Prediction of Chronic Obstructive Pulmonary Disease Complicated by Acute Lower Respiratory Tract Infection: A Cross-Sectional Study

International Journal of COPD
Jiaqi Meng,1 Weichang Yang,2 Ziyong Chen,1 Caixia Pei,1 Xinmin Peng,1 Can Li,1 Fengyuan Li1 1Department of Respiratory and Critical Care Medicine, The First Hospital of Nanchang, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi ...
Meng J, Yang W, Chen Z, Pei C, Peng X, Li C, Li F   +6 more
doaj  

Choice of therapy for coughing (spiral development)

Медицинский совет, 2019
Acute respiratory infections – the most common diseases in childhood, accompanied by cough. Treatment of cough is determined by the disease, the nature of sputum, the the general condition of the patient. The choice can be considered justified, depending
V. M. Deliagin
doaj   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

The natural history of respiratory syncytial virus in a birth cohort : the influence of age and previous infection on reinfection and disease [PDF]

, 2012
This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease.
Bottomley, C, Medley, GF, Ochola, R., Nokes, D. James, Sande, CJ, Nokes, DJ, Ochola, R, Bottomley, C., Ohuma, EO, Okiro, E. A., Medley, Graham, Sande, C. J., Cane, Patricia, Okiro, EA, Ohuma, E. O., Cane, PA   +15 more
core   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source